{"id":2834,"date":"2026-02-27T11:51:30","date_gmt":"2026-02-27T10:51:30","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&#038;p=2834"},"modified":"2026-04-15T22:55:16","modified_gmt":"2026-04-15T20:55:16","slug":"ahk-cu","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/bg\/produkt\/ahk-cu","title":{"rendered":"AHK-CU"},"content":{"rendered":"<p>AHK-Cu \u2013 v\u00fdskumn\u00fd peptidov\u00fd komplex medi<\/p>\n<p>AHK-Cu (Alan\u00edn-Histid\u00edn-Lyz\u00edn viazan\u00fd na i\u00f3n medi) je syntetick\u00fd tripeptidov\u00fd komplex medi pou\u017e\u00edvan\u00fd v experiment\u00e1lnych a preklinick\u00fdch modeloch zameran\u00fdch na bunkov\u00fa signaliz\u00e1ciu, regener\u00e1ciu tkan\u00edv a biologick\u00e9 procesy s\u00favisiace s obnovou ko\u017ee a vlasov\u00fdch folikulov. Patr\u00ed medzi tzv. copper peptides \u2013 peptidov\u00e9 komplexy schopn\u00e9 viaza\u0165 i\u00f3ny medi a modulova\u0165 redoxn\u00e9 a regenera\u010dn\u00e9 procesy v bunk\u00e1ch.<\/p>\n<p>AHK-Cu je predmetom vedeck\u00e9ho z\u00e1ujmu najm\u00e4 v oblasti dermatologick\u00e9ho v\u00fdskumu, biol\u00f3gie vlasov\u00fdch folikulov, extracelul\u00e1rnej matrice a bunkovej prolifer\u00e1cie.<\/p>\n<p>Pre\u010do je AHK-Cu predmetom v\u00fdskumu<\/p>\n<p>AHK-Cu umo\u017e\u0148uje vedcom analyzova\u0165 viacer\u00e9 biologick\u00e9 procesy:<\/p>\n<p>\u2022 regul\u00e1ciu g\u00e9novej expresie s\u00favisiacej s rastov\u00fdmi faktormi<br \/>\n\u2022 prolifer\u00e1ciu keratinocytov a derm\u00e1lnych buniek<br \/>\n\u2022 remodel\u00e1ciu extracelul\u00e1rnej matrice<br \/>\n\u2022 signaliza\u010dn\u00e9 dr\u00e1hy z\u00e1visl\u00e9 od medi<br \/>\n\u2022 biologick\u00e9 procesy s\u00favisiace s vlasov\u00fdm cyklom<\/p>\n<p>Mechanizmus p\u00f4sobenia (v\u00fdskumn\u00fd kontext)<\/p>\n<p>V experiment\u00e1lnych modeloch AHK-Cu p\u00f4sob\u00ed ako nosi\u010d i\u00f3nov medi, ktor\u00e9 zohr\u00e1vaj\u00fa d\u00f4le\u017eit\u00fa \u00falohu v bunkovej signaliz\u00e1cii, angiogen\u00e9ze a synt\u00e9ze extracelul\u00e1rnych prote\u00ednov. Me\u010f je kofaktorom viacer\u00fdch enz\u00fdmov zapojen\u00fdch do redoxn\u00fdch procesov a tvorby kolag\u00e9nu.<\/p>\n<p>Laborat\u00f3rne \u0161t\u00fadie nazna\u010duj\u00fa, \u017ee AHK-Cu m\u00f4\u017ee ovplyv\u0148ova\u0165:<\/p>\n<p>\u2022 expresiu rastov\u00fdch faktorov<br \/>\n\u2022 regul\u00e1ciu apopt\u00f3zy a bunkov\u00e9ho cyklu<br \/>\n\u2022 synt\u00e9zu kolag\u00e9nu a elast\u00ednu<br \/>\n\u2022 metabolick\u00fa aktivitu buniek ko\u017ee<\/p>\n<p>Tieto mechanizmy s\u00fa v\u00fdznamn\u00e9 pre pochopenie biologick\u00fdch procesov obnovy tkan\u00edv.<\/p>\n<p>Oblasti v\u00fdskumn\u00e9ho vyu\u017eitia<\/p>\n<p>AHK-Cu sa vyu\u017e\u00edva najm\u00e4 v oblastiach:<\/p>\n<p>\u2022 v\u00fdskum regener\u00e1cie ko\u017ee<br \/>\n\u2022 biol\u00f3gia vlasov\u00fdch folikulov<br \/>\n\u2022 v\u00fdskum extracelul\u00e1rnej matrice<br \/>\n\u2022 bunkov\u00e1 prolifer\u00e1cia a diferenci\u00e1cia<br \/>\n\u2022 molekul\u00e1rna signaliz\u00e1cia<\/p>\n<p>V\u00fdskumn\u00e9 podklady a vedeck\u00e9 zdroje<\/p>\n<p>Pou\u017eitie AHK-Cu vych\u00e1dza zo \u0161ir\u0161ieho vedeck\u00e9ho v\u00fdskumu copper peptidov a biologickej \u00falohy medi:<\/p>\n<p>1\ufe0f\u20e3 Pickart L., Thaler M.M.<br \/>\nTripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver,<br \/>\nNature, 1973<br \/>\n\u2192 Z\u00e1kladn\u00fd v\u00fdskum peptidov via\u017eucich me\u010f a ich biologick\u00fdch \u00fa\u010dinkov.<\/p>\n<p>2\ufe0f\u20e3 Pickart L.<br \/>\nThe human tri-peptide GHK and tissue remodeling,<br \/>\nJournal of Biomaterials Science, 2008<br \/>\n\u2192 Preh\u013eadov\u00fd \u010dl\u00e1nok o \u00falohe copper peptidov v remodel\u00e1cii tkan\u00edv a bunkovej signaliz\u00e1cii.<\/p>\n<p>3\ufe0f\u20e3 Farris P.K.<br \/>\nCopper peptides and skin regeneration,<br \/>\nDermatologic Surgery, 2005<br \/>\n\u2192 Klinicko-experiment\u00e1lny kontext pou\u017eitia copper peptidov vo v\u00fdskume ko\u017ee.<\/p>\n<p>4\ufe0f\u20e3 Preklinick\u00e9 modely (in vitro \/ in vivo)<br \/>\n\u0160t\u00fadie sk\u00famaj\u00face prolifer\u00e1ciu buniek, expresiu rastov\u00fdch faktorov a biologick\u00e9 procesy s\u00favisiace s vlasov\u00fdm cyklom.<\/p>\n<p>Bezpe\u010dnostn\u00e1 a regula\u010dn\u00e1 inform\u00e1cia<\/p>\n<p>\u26a0\ufe0f D\u00f4le\u017eit\u00e9 upozornenie:<\/p>\n<p>AHK-Cu je ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny a v\u00fdskumn\u00fd \u00fa\u010del.<br \/>\nNie je schv\u00e1len\u00fd ako liek.<br \/>\nNie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.<br \/>\nNie je ur\u010den\u00fd na konzum\u00e1ciu ani klinick\u00e9 aplik\u00e1cie.<\/p>\n<p>Produkt je distribuovan\u00fd v\u00fdhradne pre v\u00fdskumn\u00e9 in\u0161tit\u00facie, laborat\u00f3ri\u00e1 a odborn\u00e9 experiment\u00e1lne pou\u017eitie.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>AHK-Cu \u0435 \u0438\u0437\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0441\u043a\u0438 \u043f\u0435\u043f\u0442\u0438\u0434\u0435\u043d \u043c\u0435\u0434\u0435\u043d \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441 (\u0442\u0440\u0438\u043f\u0435\u043f\u0442\u0438\u0434 \u0430\u043b\u0430\u043d\u0438\u043d-\u0445\u0438\u0441\u0442\u0438\u0434\u0438\u043d-\u043b\u0438\u0437\u0438\u043d, \u0441\u0432\u044a\u0440\u0437\u0430\u043d \u0441 \u043c\u0435\u0434\u0435\u043d \u0439\u043e\u043d), \u0438\u0437\u043f\u043e\u043b\u0437\u0432\u0430\u043d \u0432 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u043d\u0438 \u043c\u043e\u0434\u0435\u043b\u0438 \u0437\u0430 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0435 \u043d\u0430 \u0440\u0435\u0433\u0435\u043d\u0435\u0440\u0430\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0442\u044a\u043a\u0430\u043d\u0438, \u043a\u043b\u0435\u0442\u044a\u0447\u043d\u0430\u0442\u0430 \u0441\u0438\u0433\u043d\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u044f \u0438 \u043f\u0440\u043e\u0446\u0435\u0441\u0438\u0442\u0435, \u0441\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u0441 \u0432\u044a\u0437\u0441\u0442\u0430\u043d\u043e\u0432\u044f\u0432\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u043a\u043e\u0436\u0430\u0442\u0430 \u0438 \u043a\u043e\u0441\u043c\u0435\u043d\u0438\u0442\u0435 \u0444\u043e\u043b\u0438\u043a\u0443\u043b\u0438.<\/p>\n<p>\u2705 \u0421\u0430\u043c\u043e \u0437\u0430 \u0438\u0437\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0441\u043a\u0438 \u0446\u0435\u043b\u0438<br \/>\n\u274c \u041d\u0435 \u0435 \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d \u0437\u0430 \u0445\u0443\u043c\u0430\u043d\u043d\u0430 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0430<\/p>\n","protected":false},"featured_media":2833,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[213,217],"product_tag":[],"class_list":["post-2834","product","type-product","status-publish","has-post-thumbnail","product_cat-213","product_cat-217","pa_dolezite-upozornenie-vsetky-produkty-dostupne-v-nasej-ponuke-su-urcene-vyhradne-na-vyskumne-laboratorne-a-vyvojove-ucely-nie-su-urcene-na-pouzitie-ako-liek-zdravotnicka-pomocka-kozmeticky-pripra","pa_obsah-100-","pa_obsah-50-mg","first","instock","purchasable","product-type-variable","has-default-attributes"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>AHK-CU - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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