{"id":1022,"date":"2026-03-04T10:57:23","date_gmt":"2026-03-04T09:57:23","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/product\/cardiogen"},"modified":"2026-04-15T08:15:13","modified_gmt":"2026-04-15T06:15:13","slug":"cardiogen","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/cs\/produkt\/cardiogen","title":{"rendered":"Cardiogen"},"content":{"rendered":"

Cardiogen \u2013 v\u00fdzkumn\u00fd peptidov\u00fd komplex zam\u011b\u0159en\u00fd na kardiovaskul\u00e1rn\u00ed regulaci<\/p>\n

Cardiogen je syntetick\u00fd peptidov\u00fd komplex ur\u010den\u00fd pro experiment\u00e1ln\u00ed a preklinick\u00e9 modely zam\u011b\u0159en\u00e9 na bun\u011b\u010dnou regulaci myokardu, kardiovaskul\u00e1rn\u00ed fyziologii a molekul\u00e1rn\u00ed mechanismy ovliv\u0148uj\u00edc\u00ed funkci srde\u010dn\u00ed tk\u00e1n\u011b. Pat\u0159\u00ed mezi n\u00edzkomolekul\u00e1rn\u00ed regula\u010dn\u00ed peptidy zkouman\u00e9 v oblasti bun\u011b\u010dn\u00e9 signalizace, genov\u00e9 exprese a metabolick\u00e9 aktivity kardiomyocyt\u016f.<\/p>\n

Ve v\u00fdzkumn\u00e9m kontextu je Cardiogen p\u0159edm\u011btem z\u00e1jmu zejm\u00e9na v oblasti regulace kontraktiln\u00ed funkce srdce, bun\u011b\u010dn\u00e9 adaptace na metabolick\u00fd stres a mechanism\u016f udr\u017eov\u00e1n\u00ed struktur\u00e1ln\u00ed integrity myokardu.<\/p>\n

Pro\u010d je Cardiogen p\u0159edm\u011btem v\u00fdzkumu<\/p>\n

Cardiogen umo\u017e\u0148uje v\u00fdzkumn\u00edk\u016fm analyzovat n\u011bkolik biologick\u00fdch proces\u016f, zejm\u00e9na:<\/p>\n

\u2022 regulaci genov\u00e9 exprese v kardiomyocytech
\n\u2022 mechanismy bun\u011b\u010dn\u00e9 adaptace na hypoxii a metabolick\u00fd stres
\n\u2022 signaliza\u010dn\u00ed dr\u00e1hy souvisej\u00edc\u00ed s kontraktiln\u00ed funkc\u00ed srdce
\n\u2022 metabolick\u00e9 procesy prob\u00edhaj\u00edc\u00ed v srde\u010dn\u00ed tk\u00e1ni
\n\u2022 interakci mezi mitochondri\u00e1ln\u00ed funkc\u00ed a energetickou n\u00e1ro\u010dnost\u00ed myokardu<\/p>\n

Mechanismus p\u016fsoben\u00ed (v\u00fdzkumn\u00fd kontext)<\/p>\n

V experiment\u00e1ln\u00edch modelech je Cardiogen zkoum\u00e1n jako regula\u010dn\u00ed peptid schopn\u00fd modulovat bun\u011b\u010dnou signalizaci a genovou expresi v kardi\u00e1ln\u00edm tkanivu. P\u0159edpokl\u00e1d\u00e1 se, \u017ee jeho \u00fa\u010dinek je zprost\u0159edkov\u00e1n interakc\u00ed s intracelul\u00e1rn\u00edmi regula\u010dn\u00edmi mechanismy, kter\u00e9 ovliv\u0148uj\u00ed metabolickou aktivitu a stabilitu bun\u011b\u010dn\u00fdch struktur.<\/p>\n

Laboratorn\u00ed studie nazna\u010duj\u00ed, \u017ee peptidov\u00e9 komplexy tohoto typu mohou ovliv\u0148ovat:<\/p>\n

\u2022 synt\u00e9zu protein\u016f zapojen\u00fdch do kontraktiln\u00edho apar\u00e1tu
\n\u2022 regulaci oxida\u010dn\u00edho stresu v kardiomyocytech
\n\u2022 mitochondri\u00e1ln\u00ed bioenergetiku
\n\u2022 apoptotick\u00e9 a adapta\u010dn\u00ed bun\u011b\u010dn\u00e9 dr\u00e1hy
\n\u2022 udr\u017eov\u00e1n\u00ed struktur\u00e1ln\u00ed integrity myokardu<\/p>\n

Tyto mechanismy jsou v\u00fdznamn\u00e9 pro pochopen\u00ed molekul\u00e1rn\u00ed regulace funkce srdce v experiment\u00e1ln\u00edch podm\u00ednk\u00e1ch.<\/p>\n

Oblasti v\u00fdzkumn\u00e9ho vyu\u017eit\u00ed<\/p>\n

Cardiogen se vyu\u017e\u00edv\u00e1 zejm\u00e9na v oblastech:<\/p>\n

\u2022 v\u00fdzkum kardiovaskul\u00e1rn\u00ed fyziologie
\n\u2022 bun\u011b\u010dn\u00e1 biologie kardiomyocyt\u016f
\n\u2022 experiment\u00e1ln\u00ed modely metabolick\u00e9 adaptace myokardu
\n\u2022 molekul\u00e1rn\u00ed regulace kontraktiln\u00ed funkce
\n\u2022 mitochondri\u00e1ln\u00ed bioenergetika srde\u010dn\u00ed tk\u00e1n\u011b<\/p>\n

V\u00fdzkumn\u00e9 podklady a v\u011bdeck\u00e9 zdroje<\/p>\n

Pou\u017eit\u00ed regula\u010dn\u00edch peptid\u016f v kardi\u00e1ln\u00edm v\u00fdzkumu vych\u00e1z\u00ed z \u0161ir\u0161\u00edho v\u011bdeck\u00e9ho pozn\u00e1n\u00ed bun\u011b\u010dn\u00e9 signalizace a regulace myokardu:<\/p>\n

1\ufe0f\u20e3 Olson E.N.
\nGene regulatory networks in the evolution and development of the heart
\nScience, 2006
\n\u2192 Mechanismy genov\u00e9 regulace v srde\u010dn\u00ed tk\u00e1ni.<\/p>\n

2\ufe0f\u20e3 Dorn G.W.
\nMitochondrial dynamics in heart disease
\nBiochimica et Biophysica Acta, 2013
\n\u2192 Role mitochondri\u00ed v regulaci funkce myokardu.<\/p>\n

3\ufe0f\u20e3 Heusch G.
\nThe coronary circulation as a target of cardioprotection
\nCirculation Research, 2016
\n\u2192 Mechanismy adaptace srde\u010dn\u00ed tk\u00e1n\u011b na stresov\u00e9 podn\u011bty.<\/p>\n

4\ufe0f\u20e3 Preklinick\u00e9 a in vitro modely
\nStudie zam\u011b\u0159en\u00e9 na bun\u011b\u010dnou signalizaci, genovou expresi a metabolickou regulaci v kardiomyocytech.<\/p>\n

Bezpe\u010dnostn\u00ed a regula\u010dn\u00ed informace<\/p>\n

\u26a0\ufe0f D\u016fle\u017eit\u00e9 upozorn\u011bn\u00ed:<\/p>\n

Cardiogen je ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed a v\u00fdzkumn\u00e9 \u00fa\u010dely.
\nNen\u00ed schv\u00e1len jako l\u00e9\u010divo.
\nNen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.
\nNen\u00ed ur\u010den ke konzumaci ani klinick\u00fdm aplikac\u00edm.<\/p>\n

Produkt je distribuov\u00e1n v\u00fdhradn\u011b pro v\u00fdzkumn\u00e9 instituce, laborato\u0159e a odborn\u00e9 experiment\u00e1ln\u00ed pou\u017eit\u00ed.<\/p>\n","protected":false},"excerpt":{"rendered":"

Cardiogen je syntetick\u00fd peptidov\u00fd komplex ur\u010den\u00fd pro v\u00fdzkumn\u00e9 \u00fa\u010dely v oblasti kardiovaskul\u00e1rn\u00ed fyziologie a bun\u011b\u010dn\u00e9 regulace myokardu. V experiment\u00e1ln\u00edch modelech se vyu\u017e\u00edv\u00e1 ke studiu molekul\u00e1rn\u00edch mechanism\u016f souvisej\u00edc\u00edch s funkc\u00ed srde\u010dn\u00ed tk\u00e1n\u011b, bun\u011b\u010dnou signalizac\u00ed a regulac\u00ed metabolick\u00fdch proces\u016f v kardiomyocytech.<\/p>\n

\u2705 Pouze pro v\u00fdzkumn\u00e9 \u00fa\u010dely
\n\u274c Nen\u00ed ur\u010deno pro hum\u00e1nn\u00ed pou\u017eit\u00ed<\/p>\n","protected":false},"featured_media":1023,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[155,164],"product_tag":[],"class_list":{"0":"post-1022","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-aging","7":"product_cat-regenerace","8":"pa_dolezite-upozornenie-vsechny-produkty-dostupne-v-nasi-nabidce-jsou-urceny-vyhradne-pro-vyzkumne-laboratorni-a-vyvojove-ucely-nejsou-urceny-k-pouziti-jako-lek-zdravotnicky-prostredek-kosmeticky-pripra","9":"pa_obsah-20-mg","11":"first","12":"instock","13":"purchasable","14":"product-type-simple"},"yoast_head":"\nCardiogen - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/cs\/produkt\/cardiogen\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cardiogen - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"Cardiogen je syntetick\u00fd peptidov\u00fd komplex ur\u010den\u00fd pro v\u00fdzkumn\u00e9 \u00fa\u010dely v oblasti kardiovaskul\u00e1rn\u00ed fyziologie a bun\u011b\u010dn\u00e9 regulace myokardu. 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