{"id":7675,"date":"2026-06-16T21:55:12","date_gmt":"2026-06-16T19:55:12","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&p=7675"},"modified":"2026-07-20T10:41:54","modified_gmt":"2026-07-20T08:41:54","slug":"ss-31-pen-50mg","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/cs\/produkt\/ss-31-pen-50mg","title":{"rendered":"SS-31 pen 50mg"},"content":{"rendered":"

SS-31 \u2013 d\u00e1vkovac\u00ed pero 50mg\/2ml (Mitochondria-Targeting Antioxidant Peptide \/ Elamipretide)<\/strong><\/p>\n

SS-31 (chemicky D-Arg-Dmt-Lys-Phe-NH2, zn\u00e1m\u00fd pod n\u00e1zvy Elamipretide nebo Bendavia) p\u0159edstavuje zcela novou t\u0159\u00eddu mal\u00fdch experiment\u00e1ln\u00edch peptid\u016f c\u00edlen\u00fdch p\u0159\u00edmo na mitochondrie. Na rozd\u00edl od standardn\u00edch antioxidant\u016f, kter\u00e9 nedok\u00e1\u017eou efektivn\u011b pronikat p\u0159es bun\u011b\u010dn\u00e9 bari\u00e9ry, SS-31 d\u00edky sv\u00e9mu specifick\u00e9mu n\u00e1boji p\u016fsob\u00ed p\u0159\u00edmo na vnit\u0159n\u00ed mitochondri\u00e1ln\u00ed membr\u00e1nu. V modern\u00edm biomedic\u00ednsk\u00e9m v\u00fdzkumu a oblasti longevity je tato molekula pova\u017eov\u00e1na za pr\u016flomovou, jeliko\u017e c\u00edlen\u011b \u0159e\u0161\u00ed mitochondri\u00e1ln\u00ed dysfunkci \u2013 jeden z hlavn\u00edch spou\u0161t\u011b\u010d\u016f bun\u011b\u010dn\u00e9ho st\u00e1rnut\u00ed, degenerativn\u00edch onemocn\u011bn\u00ed a energetick\u00e9ho vy\u010derp\u00e1n\u00ed bun\u011bk.<\/p>\n

D\u00e1vkovac\u00ed pero obsahuje 50 mg vysoce \u010dist\u00e9 a stabilizovan\u00e9 \u00fa\u010dinn\u00e9 l\u00e1tky ve 2 ml roztoku, co\u017e p\u0159edstavuje koncentraci p\u0159esn\u011b 25 mg\/ml. P\u0159epo\u010det pro p\u0159esn\u00e9 d\u00e1vkov\u00e1n\u00ed v r\u00e1mci v\u00fdzkumn\u00fdch protokol\u016f:<\/p>\n

1 ml = 100 jednotek (UI) = 100 kliknut\u00ed<\/p>\n

0,5 ml (jedno pln\u00e9 oto\u010den\u00ed mechanismu) = 50 kliknut\u00ed<\/p>\n

P\u0159\u00edklady d\u00e1vkov\u00e1n\u00ed pro v\u00fdzkumn\u00e9 \u00fa\u010dely:<\/p>\n

1 kliknut\u00ed = 0,25 mg \u00fa\u010dinn\u00e9 l\u00e1tky<\/p>\n

2 kliknut\u00ed = 0,50 mg \u00fa\u010dinn\u00e9 l\u00e1tky<\/p>\n

4 kliknut\u00ed = 1,00 mg \u00fa\u010dinn\u00e9 l\u00e1tky<\/p>\n

10 kliknut\u00ed (0,1 ml) = 2,50 mg \u00fa\u010dinn\u00e9 l\u00e1tky<\/p>\n

20 kliknut\u00ed (0,2 ml) = 5,00 mg \u00fa\u010dinn\u00e9 l\u00e1tky<\/p>\n

40 kliknut\u00ed (0,4 ml) = 10,00 mg \u00fa\u010dinn\u00e9 l\u00e1tky<\/p>\n

Tento mechanick\u00fd syst\u00e9m zaru\u010duje absolutn\u00ed p\u0159esnost, opakovatelnost a flexibilitu p\u0159i nastavov\u00e1n\u00ed mikrod\u00e1vek podle pot\u0159eb konkr\u00e9tn\u00edho laboratorn\u00edho protokolu bez nutnosti slo\u017eit\u00e9ho a chybami zat\u00ed\u017een\u00e9ho ru\u010dn\u00edho \u0159ed\u011bn\u00ed.<\/p>\n

\u00da\u010dinky zkouman\u00e9 v\u00fdzkumem<\/strong><\/p>\n

Prim\u00e1rn\u00edm a nejv\u00fdznamn\u011bj\u0161\u00edm mechanismem \u00fa\u010dinku SS-31, kter\u00fd v\u011bdci podrobn\u011b zkoumaj\u00ed, je jeho selektivn\u00ed vazba na kardiolipin \u2013 unik\u00e1tn\u00ed fosfolipid nach\u00e1zej\u00edc\u00ed se v\u00fdhradn\u011b ve vnit\u0159n\u00ed mitochondri\u00e1ln\u00ed membr\u00e1n\u011b. Kardiolipin ukotvuje proteinov\u00e9 komplexy d\u00fdchac\u00edho \u0159et\u011bzce odpov\u011bdn\u00e9 za produkci energie. P\u0159i oxida\u010dn\u00edm stresu doch\u00e1z\u00ed k po\u0161kozen\u00ed kardiolipinu, co\u017e vede k naru\u0161en\u00ed struktury membr\u00e1ny a \u00faniku voln\u00fdch radik\u00e1l\u016f (ROS). SS-31 prokazateln\u011b stabilizuje kardiolipin, \u010d\u00edm\u017e p\u0159\u00edmo obnovuje architekturu vnit\u0159n\u00ed membr\u00e1ny (kristy).<\/p>\n

Tento proces vede k okam\u017eit\u00e9 optimalizaci produkce ATP (bun\u011b\u010dn\u00e9 energie) a drastick\u00e9mu sn\u00ed\u017een\u00ed tvorby \u0161kodliv\u00fdch reaktivn\u00edch forem kysl\u00edku p\u0159\u00edmo u jejich zdroje. Ve studi\u00edch in vivo vykazuje SS-31 mimo\u0159\u00e1dn\u00fd potenci\u00e1l p\u0159i ochran\u011b p\u0159ed ischemicko-reperfuzn\u00edm po\u0161kozen\u00edm (nap\u0159. p\u0159i infarktu myokardu nebo akutn\u00edm po\u0161kozen\u00ed ledvin), kdy rychle br\u00e1n\u00ed bun\u011b\u010dn\u00e9 smrti (apopt\u00f3ze). Velmi slibn\u00fd v\u00fdzkum prob\u00edh\u00e1 tak\u00e9 v oblasti neurodegenerativn\u00edch onemocn\u011bn\u00ed (jako jsou Alzheimerova a Parkinsonova choroba \u010di s v\u011bkem spojen\u00fd kognitivn\u00ed \u00fapadek), svalov\u00e9 atrofie a chronick\u00e9 \u00fanavy, kde obnova mitochondri\u00e1ln\u00edho zdrav\u00ed vykazuje z\u00e1sadn\u00ed zlep\u0161en\u00ed motorick\u00fdch a ment\u00e1ln\u00edch funkc\u00ed subjekt\u016f.<\/p>\n

V\u011bdeck\u00fd kontext a zdroje<\/strong><\/p>\n

Molekula SS-31 byla rozs\u00e1hle testov\u00e1na v pokro\u010dil\u00fdch klinick\u00fdch i preklinick\u00fdch studi\u00edch zam\u011b\u0159en\u00fdch na metabolick\u00e9, kardiologick\u00e9 a mitochondri\u00e1ln\u00ed patologie. Stovky odborn\u00fdch recenzovan\u00fdch prac\u00ed podrobn\u011b mapuj\u00edc\u00edch jej\u00ed interakci s bioenergetick\u00fdmi drahami bu\u0148ky jsou voln\u011b dostupn\u00e9 v respektovan\u00e9 mezin\u00e1rodn\u00ed datab\u00e1zi PubMed.<\/p>\n

P\u0159esn\u00e9 informace o farmakokinetice, vlivu elamipretidu na funkci kostern\u00edho svalstva, sn\u00ed\u017een\u00ed nitrobun\u011b\u010dn\u00e9ho z\u00e1n\u011btu a ochran\u011b c\u00e9vn\u00edho endotelu jsou pr\u016fb\u011b\u017en\u011b shroma\u017e\u010fov\u00e1ny v akademick\u00fdch registrech na ClinicalTrials.gov, kde tato l\u00e1tka p\u0159edstavuje kl\u00ed\u010dov\u00fd model pro v\u00fdvoj budouc\u00edch pokro\u010dil\u00fdch terapi\u00ed zalo\u017een\u00fdch na mitochondri\u00e1ln\u00ed medic\u00edn\u011b.<\/p>\n

D\u00e1vkovac\u00ed pero od Royal Peptides poskytuje modern\u00ed, bezpe\u010dn\u00e9 a vysoce steriln\u00ed \u0159e\u0161en\u00ed pro manipulaci s touto pokro\u010dilou molekulou v kontrolovan\u00fdch laboratorn\u00edch podm\u00ednk\u00e1ch.<\/p>\n

Produkt je ur\u010den v\u00fdhradn\u011b pro v\u011bdeck\u00e9 a v\u00fdzkumn\u00e9 \u00fa\u010dely. Nen\u00ed ur\u010den k p\u0159\u00edm\u00e9 konzumaci.<\/p>\n","protected":false},"excerpt":{"rendered":"

D\u00e1vkovac\u00ed pero Royal Peptides \u2013 SS-31 50mg\/2ml<\/strong> Modern\u00ed a praktick\u00e9 d\u00e1vkovac\u00ed pero navr\u017een\u00e9 pro p\u0159esn\u00e9 a pohodln\u00e9 d\u00e1vkov\u00e1n\u00ed v\u00fdzkumn\u00fdch slou\u010denin. Elegantn\u00ed design, kompaktn\u00ed proveden\u00ed a jednoduch\u00e9 ovl\u00e1d\u00e1n\u00ed umo\u017e\u0148uj\u00ed efektivn\u00ed manipulaci v laboratorn\u00edm prost\u0159ed\u00ed. SS-31 (Elamipretide) je inovativn\u00ed syntetick\u00fd tetrapeptid c\u00edlen\u00fd p\u0159\u00edmo na mitochondrie, kter\u00fd vykazuje mimo\u0159\u00e1dn\u011b siln\u00e9 cytoprotektivn\u00ed a antioxida\u010dn\u00ed vlastnosti. Je p\u0159edm\u011btem intenzivn\u00edho v\u011bdeck\u00e9ho v\u00fdzkumu v oblasti obnovy funkce mitochondri\u00e1ln\u00edch membr\u00e1n, radik\u00e1ln\u00edho potla\u010den\u00ed nitrobun\u011b\u010dn\u00e9ho oxida\u010dn\u00edho stresu, optimalizace produkce ATP energie a ochrany org\u00e1n\u016f p\u0159ed ischemicko-reperfuzn\u00edm po\u0161kozen\u00edm. Jehly nejsou sou\u010d\u00e1st\u00ed balen\u00ed ani nejsou v na\u0161\u00ed nab\u00eddce. Produkt je ur\u010den v\u00fdhradn\u011b pro v\u011bdeck\u00e9 a v\u00fdzkumn\u00e9 \u00fa\u010dely.<\/p>\n","protected":false},"featured_media":7674,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[158,160,301],"product_tag":[],"class_list":["post-7675","product","type-product","status-publish","has-post-thumbnail","product_cat-fitness","product_cat-hormonalni-rovnovaha","product_cat-doplnky","first","instock","purchasable","product-type-simple"],"yoast_head":"\nSS-31 pen 50mg - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/cs\/produkt\/ss-31-pen-50mg\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SS-31 pen 50mg - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"D\u00e1vkovac\u00ed pero Royal Peptides \u2013 SS-31 50mg\/2ml Modern\u00ed a praktick\u00e9 d\u00e1vkovac\u00ed pero navr\u017een\u00e9 pro p\u0159esn\u00e9 a pohodln\u00e9 d\u00e1vkov\u00e1n\u00ed v\u00fdzkumn\u00fdch slou\u010denin. Elegantn\u00ed design, kompaktn\u00ed proveden\u00ed a jednoduch\u00e9 ovl\u00e1d\u00e1n\u00ed umo\u017e\u0148uj\u00ed efektivn\u00ed manipulaci v laboratorn\u00edm prost\u0159ed\u00ed. SS-31 (Elamipretide) je inovativn\u00ed syntetick\u00fd tetrapeptid c\u00edlen\u00fd p\u0159\u00edmo na mitochondrie, kter\u00fd vykazuje mimo\u0159\u00e1dn\u011b siln\u00e9 cytoprotektivn\u00ed a antioxida\u010dn\u00ed vlastnosti. Je p\u0159edm\u011btem intenzivn\u00edho v\u011bdeck\u00e9ho v\u00fdzkumu v oblasti obnovy funkce mitochondri\u00e1ln\u00edch membr\u00e1n, radik\u00e1ln\u00edho potla\u010den\u00ed nitrobun\u011b\u010dn\u00e9ho oxida\u010dn\u00edho stresu, optimalizace produkce ATP energie a ochrany org\u00e1n\u016f p\u0159ed ischemicko-reperfuzn\u00edm po\u0161kozen\u00edm. Jehly nejsou sou\u010d\u00e1st\u00ed balen\u00ed ani nejsou v na\u0161\u00ed nab\u00eddce. 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Elegantn\u00ed design, kompaktn\u00ed proveden\u00ed a jednoduch\u00e9 ovl\u00e1d\u00e1n\u00ed umo\u017e\u0148uj\u00ed efektivn\u00ed manipulaci v laboratorn\u00edm prost\u0159ed\u00ed. SS-31 (Elamipretide) je inovativn\u00ed syntetick\u00fd tetrapeptid c\u00edlen\u00fd p\u0159\u00edmo na mitochondrie, kter\u00fd vykazuje mimo\u0159\u00e1dn\u011b siln\u00e9 cytoprotektivn\u00ed a antioxida\u010dn\u00ed vlastnosti. Je p\u0159edm\u011btem intenzivn\u00edho v\u011bdeck\u00e9ho v\u00fdzkumu v oblasti obnovy funkce mitochondri\u00e1ln\u00edch membr\u00e1n, radik\u00e1ln\u00edho potla\u010den\u00ed nitrobun\u011b\u010dn\u00e9ho oxida\u010dn\u00edho stresu, optimalizace produkce ATP energie a ochrany org\u00e1n\u016f p\u0159ed ischemicko-reperfuzn\u00edm po\u0161kozen\u00edm. Jehly nejsou sou\u010d\u00e1st\u00ed balen\u00ed ani nejsou v na\u0161\u00ed nab\u00eddce. 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