KPV (Lys-Pro-Val) je kr\u00e1tky syntetick\u00fd tripeptid odvoden\u00fd z alfa-melanocyt stimuluj\u00faceho horm\u00f3nu (\u03b1-MSH). Vo vedeckom v\u00fdskume je predmetom z\u00e1ujmu najm\u00e4 pre svoje protiz\u00e1palov\u00e9 a imunomodula\u010dn\u00e9 vlastnosti, ktor\u00e9 sa sk\u00famaj\u00fa v preklinick\u00fdch a laborat\u00f3rnych modeloch.<\/p>\n
V experimentoch sa KPV pou\u017e\u00edva ako n\u00e1stroj na anal\u00fdzu bunkov\u00fdch sign\u00e1lnych dr\u00e1h, regul\u00e1cie cytok\u00ednov a procesov spojen\u00fdch so z\u00e1palom a regener\u00e1ciou tkan\u00edv.<\/p>\n
\u26a0\ufe0f KPV je ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny a vedeck\u00fd v\u00fdskum.
\n\u26a0\ufe0f Nie je to liek a nie je schv\u00e1len\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.<\/p>\n
Pre\u010do v\u00fdskumn\u00edci KPV \u0161tuduj\u00fa?
\nKPV je predmetom v\u00fdskumu najm\u00e4 pre tieto vlastnosti:<\/p>\n
\u2022 Podpora protiz\u00e1palov\u00fdch mechanizmov na bunkovej \u00farovni
\n\u2022 Modul\u00e1cia imunitnej odpovede v experiment\u00e1lnych modeloch
\n\u2022 Regul\u00e1cia produkcie z\u00e1palov\u00fdch cytok\u00ednov
\n\u2022 \u0160t\u00fadium regener\u00e1cie buniek v z\u00e1palovom prostred\u00ed<\/p>\n
Tieto vlastnosti robia z KPV cenn\u00fd n\u00e1stroj pre v\u00fdskum imunitn\u00fdch a z\u00e1palov\u00fdch procesov.<\/p>\n
Ako KPV p\u00f4sob\u00ed v laborat\u00f3rnych podmienkach?
\nV preklinick\u00fdch \u0161t\u00fadi\u00e1ch sa ukazuje, \u017ee KPV interaguje s imunitn\u00fdmi bunkami a ovplyv\u0148uje signaliza\u010dn\u00e9 dr\u00e1hy spojen\u00e9 so z\u00e1palom. V\u00fdskumn\u00edci sleduj\u00fa jeho schopnos\u0165 regulova\u0165 aktivitu cytok\u00ednov, stabilizova\u0165 bunkov\u00e9 prostredie a podporova\u0165 procesy obnovy tkan\u00edv.<\/p>\n
Mechanizmus \u00fa\u010dinku sa sk\u00fama najm\u00e4 v in vitro (bunkov\u00fdch) a preklinick\u00fdch modeloch.<\/p>\n
V\u00fdskumn\u00e9 podklady
\nNieko\u013eko vedeck\u00fdch publik\u00e1ci\u00ed poukazuje na biologick\u00fd potenci\u00e1l KPV:<\/p>\n
\u2022 Lee M. et al., Journal of Immunology, 2008
\n\u0160t\u00fadie protiz\u00e1palov\u00fdch \u00fa\u010dinkov KPV a jeho vplyvu na imunitn\u00fa odpove\u010f.<\/p>\n
\u2022 Preklinick\u00e9 modely
\nPozorovan\u00e9 \u00fa\u010dinky na regul\u00e1ciu z\u00e1palov\u00fdch procesov a imunitn\u00fa modul\u00e1ciu.<\/p>\n
Tieto v\u00fdskumy potvrdzuj\u00fa biologick\u00fa aktivitu KPV na bunkovej \u00farovni, pri\u010dom klinick\u00e9 vyu\u017eitie u \u013eud\u00ed zost\u00e1va predmetom \u010fal\u0161ieho v\u00fdskumu.<\/p>\n
\u26a0\ufe0f Bezpe\u010dnostn\u00e1 a regula\u010dn\u00e1 pozn\u00e1mka
\n\u2022 KPV je v\u00fdhradne v\u00fdskumn\u00fd peptid
\n\u2022 \u274c Nie je schv\u00e1len\u00fd ako liek ani zdravotn\u00edcka pom\u00f4cka
\n\u2022 \u274c Nie je ur\u010den\u00fd na aplik\u00e1ciu na \u013eu\u010foch ani zvierat\u00e1ch
\n\u2022 \u2705 Ur\u010den\u00fd v\u00fdlu\u010dne pre laborat\u00f3rny a experiment\u00e1lny v\u00fdskum<\/p>\n","protected":false},"excerpt":{"rendered":"
KPV je v\u00fdskumn\u00fd peptid sk\u00famaj\u00faci protiz\u00e1palov\u00e9 mechanizmy a imunitn\u00fa regul\u00e1ciu. Pou\u017e\u00edva sa v laborat\u00f3rnych modeloch na \u0161t\u00fadium z\u00e1palov\u00fdch procesov a bunkovej obnovy. Ur\u010den\u00fd v\u00fdhradne pre vedeck\u00fd v\u00fdskum, nie je schv\u00e1len\u00fd na hum\u00e1nne pou\u017eitie.<\/p>\n
Obsah:<\/strong> 10mg<\/p>\n","protected":false},"featured_media":1271,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[161,165],"product_tag":[],"class_list":["post-1270","product","type-product","status-publish","has-post-thumbnail","product_cat-hormonal-balance","product_cat-regeneration","pa_dolezite-upozornenie-vsetky-produkty-dostupne-v-nasej-ponuke-su-urcene-vyhradne-na-vyskumne-laboratorne-a-vyvojove-ucely-nie-su-urcene-na-pouzitie-ako-liek-zdravotnicka-pomocka-kozmeticky-pripra","pa_obsah-10mg","first","instock","purchasable","product-type-simple"],"yoast_head":"\n