CJC-1295 Without DAC \u2013 v\u00fdskumn\u00fd peptid pre \u0161t\u00fadium regul\u00e1cie rastov\u00e9ho horm\u00f3nu
\n(Research Use Only)<\/p>\n
CJC-1295 Without DAC je syntetick\u00fd anal\u00f3g horm\u00f3nu uvo\u013e\u0148uj\u00faceho rastov\u00fd horm\u00f3n (GHRH \u2013 Growth Hormone Releasing Hormone), navrhnut\u00fd pre laborat\u00f3rny a experiment\u00e1lny v\u00fdskum. Tento peptid stimuluje endog\u00e9nnu sekr\u00e9ciu rastov\u00e9ho horm\u00f3nu (GH) prostredn\u00edctvom aktiv\u00e1cie GHRH receptorov a umo\u017e\u0148uje presn\u00e9 \u0161t\u00fadium hormon\u00e1lnych regula\u010dn\u00fdch mechanizmov.<\/p>\n
Na rozdiel od variantov viazan\u00fdch na DAC (Drug Affinity Complex) m\u00e1 CJC-1295 Without DAC krat\u0161\u00ed biologick\u00fd pol\u010das, \u010do vedie k prirodzenej\u0161iemu pulzn\u00e9mu profilu uvo\u013e\u0148ovania GH. T\u00e1to vlastnos\u0165 je mimoriadne cenn\u00e1 pre v\u00fdskumn\u00e9 modely, ktor\u00e9 analyzuj\u00fa fyziologick\u00e9 hormon\u00e1lne rytmy.<\/p>\n
Mechanistick\u00fd profil
\nAktiv\u00e1cia GHRH receptora
\nCJC-1295 Without DAC stimuluje uvo\u013e\u0148ovanie rastov\u00e9ho horm\u00f3nu prostredn\u00edctvom priamej aktiv\u00e1cie receptorov GHRH v hypofyz\u00e1rnych modeloch.<\/p>\n
\u2699 Pulzn\u00fd efekt uvo\u013e\u0148ovania GH
\nKr\u00e1tkodob\u00e1 a selekt\u00edvna stimul\u00e1cia umo\u017e\u0148uje simulova\u0165 prirodzen\u00e9 pulzy rastov\u00e9ho horm\u00f3nu, \u010do je d\u00f4le\u017eit\u00e9 pre v\u00fdskum endog\u00e9nnej hormon\u00e1lnej regul\u00e1cie.<\/p>\n
Metabolick\u00e1 a regenera\u010dn\u00e1 signaliz\u00e1cia
\nV preklinick\u00fdch \u0161t\u00fadi\u00e1ch sa CJC-1295 Without DAC vyu\u017e\u00edva na sk\u00famanie metabolick\u00fdch dr\u00e1h, bunkovej regener\u00e1cie a procesov obnovy tkan\u00edv.<\/p>\n
Bez DAC komplexu
\nAbsencia DAC umo\u017e\u0148uje presnej\u0161ie \u010dasov\u00e9 riadenie experimentov a flexibilnej\u0161ie modelovanie hormon\u00e1lnych odpoved\u00ed.<\/p>\n
V\u00fdhody pre v\u00fdskum
\nCJC-1295 Without DAC sa v laborat\u00f3rnej praxi vyu\u017e\u00edva najm\u00e4 pre:<\/p>\n
\u0161t\u00fadium regul\u00e1cie rastov\u00e9ho horm\u00f3nu<\/p>\n
anal\u00fdzu pulzn\u00fdch hormon\u00e1lnych mechanizmov<\/p>\n
v\u00fdskum metabolick\u00fdch procesov<\/p>\n
modelovanie bunkovej regener\u00e1cie<\/p>\n
sk\u00famanie hormon\u00e1lnych sign\u00e1lnych dr\u00e1h<\/p>\n
V\u00fdskumn\u00e9 podklady
\nBiologick\u00e1 aktivita CJC-1295 bola predmetom viacer\u00fdch odborn\u00fdch \u0161t\u00fadi\u00ed:<\/p>\n
Tevfik F. et al., Journal of Clinical Endocrinology & Metabolism (2003)
\nAnal\u00fdza \u00fa\u010dinkov CJC-1295 na uvo\u013e\u0148ovanie GH a IGF-1.<\/p>\n
Ghigo E. et al., Endocrine Reviews (2005)
\nPreh\u013ead mechanizmov pulznej regul\u00e1cie rastov\u00e9ho horm\u00f3nu.<\/p>\n
Preklinick\u00e9 modely poukazuj\u00fa na vyu\u017eitie CJC-1295 Without DAC pri \u0161t\u00fadiu rastu svalov\u00e9ho tkaniva a bunkovej obnovy v experiment\u00e1lnych podmienkach.<\/p>\n
Pou\u017eitie vo v\u00fdskume
\nCJC-1295 Without DAC sa v laborat\u00f3rnych podmienkach vyu\u017e\u00edva najm\u00e4 na:<\/p>\n
anal\u00fdzu endog\u00e9nnej regul\u00e1cie GH<\/p>\n
v\u00fdskum metabolizmu a energetickej rovnov\u00e1hy<\/p>\n
\u0161t\u00fadium regenera\u010dn\u00fdch procesov<\/p>\n
hormon\u00e1lne modelovanie a signaliz\u00e1ciu<\/p>\n
experiment\u00e1lne bunkov\u00e9 \u0161t\u00fadie<\/p>\n
Bezpe\u010dnostn\u00e1 a regula\u010dn\u00e1 inform\u00e1cia
\nCJC-1295 Without DAC je klasifikovan\u00fd ako v\u00fdskumn\u00fd peptid.<\/p>\n
\u274c Nie je schv\u00e1len\u00fd ako liek<\/p>\n
\u274c Nie je ur\u010den\u00fd na diagnostiku<\/p>\n
\u274c Nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie<\/p>\n
\u2705 Ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny a vedeck\u00fd v\u00fdskum<\/p>\n
Zak\u00fapen\u00edm produktu z\u00e1kazn\u00edk potvrdzuje, \u017ee rozumie jeho v\u00fdskumn\u00e9mu charakteru a zav\u00e4zuje sa pou\u017e\u00edva\u0165 ho v\u00fdlu\u010dne v s\u00falade s t\u00fdmto ur\u010den\u00edm.<\/p>\n","protected":false},"excerpt":{"rendered":"
CJC-1295 Without DAC je v\u00fdskumn\u00fd peptid pou\u017e\u00edvan\u00fd v laborat\u00f3rnych \u0161t\u00fadi\u00e1ch regul\u00e1cie rastov\u00e9ho horm\u00f3nu (GH). V preklinickom v\u00fdskume sa vyu\u017e\u00edva na anal\u00fdzu pulznej sekr\u00e9cie GH, metabolick\u00fdch procesov a bunkovej regener\u00e1cie. Produkt je ur\u010den\u00fd v\u00fdhradne na vedeck\u00e9 a experiment\u00e1lne \u00fa\u010dely.<\/p>\n","protected":false},"featured_media":1385,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[159,161,165,157],"product_tag":[],"class_list":{"0":"post-1384","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-fitness","7":"product_cat-hormonal-balance","8":"product_cat-regeneration","9":"product_cat-weight-loss","10":"pa_dolezite-upozornenie-vsetky-produkty-dostupne-v-nasej-ponuke-su-urcene-vyhradne-na-vyskumne-laboratorne-a-vyvojove-ucely-nie-su-urcene-na-pouzitie-ako-liek-zdravotnicka-pomocka-kozmeticky-pripra","11":"pa_obsah-10mg","12":"pa_obsah-5mg","14":"first","15":"instock","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"yoast_head":"\n