PEG-MGF \u2013 research peptide (pegylated mechano growth factor)
\n(Research Use Only)<\/p>\n
PEG-MGF is a synthetic pegylated form of mechano growth factor (MGF), which represents an isoform of insulin-like growth factor 1 (IGF-1). Pegylation (attachment of a PEG chain) extends its stability and biological availability under experimental conditions, allowing for more detailed investigation of its effects.<\/p>\n
In scientific and preclinical studies, PEG-MGF is used as a tool for analyzing muscle regeneration, cellular proliferation, and adaptive processes to mechanical load.<\/p>\n
Mechanistic profile<\/p>\n
IGF-1 isoform (Mechano Growth Factor)
\nPEG-MGF is derived from a naturally occurring isoform of IGF-1 that is activated in response to mechanical damage of muscle tissue.<\/p>\n
Satellite cell activation
\nIn laboratory models, its ability to activate muscle satellite cells is studied, as these play a key role in muscle regeneration.<\/p>\n
Muscle regeneration
\nPreclinical studies examine its effect on the repair of damaged muscle fibers and tissue restoration.<\/p>\n
\u2699 Extended biological activity
\nPegylation allows for prolonged action of the molecule under experimental conditions, expanding the possibilities for studying time-dependent effects.<\/p>\n
Cellular proliferation and differentiation
\nResearch focuses on its role in regulating cell growth and their differentiation in muscle tissue.<\/p>\n
Research advantages<\/p>\n
PEG-MGF is mainly used in the areas of:<\/p>\n
study of muscle regeneration
\nanalysis of satellite cell activation
\nresearch of IGF-1 signaling pathways
\nmodeling of adaptive processes to mechanical load
\nstudy of cellular proliferation and differentiation<\/p>\n
Scientific background<\/p>\n
The biological properties of MGF and its derivatives have been the subject of several scientific studies:<\/p>\n
Goldspink G., Journal of Physiology \u2013 identification of MGF as a mechanically induced isoform of IGF-1 and its role in muscle adaptation
\nYang SY et al., Journal of Muscle Research and Cell Motility \u2013 MGF stimulates satellite cell activation and muscle regeneration
\nPhilippou A et al., Growth Hormone & IGF Research \u2013 role of IGF-1 isoforms in regulating muscle growth and tissue repair
\nHill M., Goldspink G., Journal of Physiology \u2013 mechanisms of muscle growth regulation via IGF-1 and MGF
\nExperimental studies suggest that pegylated forms of peptides may extend biological activity and stability under laboratory conditions<\/p>\n
Use in research<\/p>\n
PEG-MGF is used in laboratory conditions mainly for:<\/p>\n
muscle regeneration research
\nanalysis of IGF-1\/MGF signaling pathways
\nstudy of cellular proliferation
\nmodeling of muscle tissue damage and repair
\nexperimental cellular and preclinical studies<\/p>\n
Safety and regulatory information<\/p>\n
PEG-MGF is classified as a research peptide.<\/p>\n
\u274c Not approved as a medicinal product
\n\u274c Not intended for diagnostic use
\n\u274c Not intended for human or veterinary use<\/p>\n
\u2705 Intended exclusively for laboratory and scientific research<\/p>\n
By purchasing the product, the customer confirms that they understand its research nature and agree to use it exclusively in accordance with this intended purpose.<\/p>\n","protected":false},"excerpt":{"rendered":"
PEG-MGF is a research peptide \u2013 a pegylated form of mechano growth factor (MGF), used in laboratory studies focused on muscle regeneration and cellular proliferation. In preclinical research, its effects on satellite cell activation, muscle fiber repair, and processes related to adaptation to mechanical load are being investigated. The product is intended exclusively for scientific purposes.<\/p>\n","protected":false},"featured_media":3958,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[154,159,165],"product_tag":[],"class_list":{"0":"post-3959","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-aging","7":"product_cat-fitness","8":"product_cat-regeneration","9":"pa_obsah-2mg","11":"first","12":"instock","13":"purchasable","14":"product-type-simple"},"yoast_head":"\n