Follistatin \u2013 research protein (regulator of TGF-\u03b2 pathways)
\n(Research Use Only)<\/p>\n
Follistatin is a naturally occurring glycoprotein that binds to and inhibits members of the TGF-\u03b2 family, particularly myostatin and activin. These factors play an important role in the regulation of muscle tissue growth, cellular proliferation, and differentiation.<\/p>\n
In scientific and preclinical studies, Follistatin is used as a tool to analyze the mechanisms of growth factor regulation, muscle regeneration, and tissue development.<\/p>\n
Mechanistic profile<\/p>\n
Myostatin and activin inhibitor
\nFollistatin binds to myostatin and activin, blocking their biological activity and enabling the study of their regulatory functions.<\/p>\n
Regulation of muscle growth
\nIn laboratory models, its effect on muscle tissue growth is monitored through the inhibition of myostatin, which normally limits muscle growth.<\/p>\n
Muscle regeneration
\nPreclinical studies examine its role in the repair of damaged muscle fibers and tissue regeneration.<\/p>\n
\u2699 Cellular proliferation and differentiation
\nResearch focuses on its ability to regulate cell growth and their differentiation in various tissues.<\/p>\n
TGF-\u03b2 signaling pathways
\nFollistatin enables detailed investigation of TGF-\u03b2 family signaling pathways, which are essential for organism development and homeostasis.<\/p>\n
Benefits for research<\/p>\n
Follistatin is primarily used in areas such as:<\/p>\n
study of muscle growth and regeneration
\nanalysis of myostatin signaling
\nresearch of TGF-\u03b2 pathways
\nstudy of cellular proliferation and differentiation
\nmodeling of tissue development<\/p>\n
Scientific background<\/p>\n
The biological properties of Follistatin have been the subject of multiple scientific studies:<\/p>\n
Lee SJ, McPherron AC., Proceedings of the National Academy of Sciences (PNAS) \u2013 identification of myostatin as a negative regulator of muscle growth
\nAmthor H et al., Nature \u2013 inhibition of myostatin leads to increased muscle mass in experimental models
\nPhillips DJ, de Kretser DM., Endocrine Reviews \u2013 role of activin and follistatin in the regulation of reproductive and growth processes
\nHansen JS et al., Journal of Applied Physiology \u2013 studies indicating the role of follistatin in muscle adaptation and metabolism
\nExperimental models suggest that modulation of TGF-\u03b2 pathways affects tissue growth and regeneration<\/p>\n
Use in research<\/p>\n
Follistatin is used in laboratory settings mainly for:<\/p>\n
research of muscle growth
\nanalysis of myostatin and activin signaling
\nstudy of tissue regeneration
\nmodeling of cellular proliferation
\nexperimental cell and preclinical studies<\/p>\n
Safety and regulatory information<\/p>\n
Follistatin is classified as a research protein.<\/p>\n
\u274c Not approved as a medicinal product
\n\u274c Not intended for diagnostic use
\n\u274c Not intended for human or veterinary use<\/p>\n
\u2705 Intended exclusively for laboratory and scientific research<\/p>\n
By purchasing the product, the customer confirms that they understand its research nature and agree to use it strictly in accordance with this purpose.<\/p>\n","protected":false},"excerpt":{"rendered":"
Follistatin is a research protein \u2013 a glycoprotein that binds members of the TGF-\u03b2 family, used in laboratory studies focused on the regulation of growth factors and cellular proliferation. In preclinical research, its effects on myostatin inhibition, muscle regeneration, and tissue differentiation processes are studied. The product is intended exclusively for scientific purposes.<\/p>\n","protected":false},"featured_media":3964,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[154,159,161,165],"product_tag":[],"class_list":{"0":"post-3965","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-aging","7":"product_cat-fitness","8":"product_cat-hormonal-balance","9":"product_cat-regeneration","10":"pa_obsah-1mg","12":"first","13":"instock","14":"purchasable","15":"product-type-simple"},"yoast_head":"\n