{"id":7971,"date":"2026-06-16T21:55:12","date_gmt":"2026-06-16T19:55:12","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&#038;p=7971"},"modified":"2026-07-19T15:41:07","modified_gmt":"2026-07-19T13:41:07","slug":"nad-pen-500mg","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/en\/product\/nad-pen-500mg","title":{"rendered":"NAD+ pen 500mg"},"content":{"rendered":"<p><strong>NAD+ \u2013 Dosing Pen 500mg\/2ml (Cellular Coenzyme)<\/strong><\/p>\n<p>NAD+ is a key coenzyme and redox cofactor that plays an irreplaceable role in the organism in electron transfer and cellular energy production. With increasing age, the level of naturally occurring NAD+ in tissues decreases dramatically, which in modern biomedical research is considered one of the main triggers of mitochondrial dysfunction and cellular aging. This experimental compound is therefore the subject of intensive studies aimed at reversing these effects through activation of sirtuins (so-called \u201clongevity genes\u201d) and enzymes involved in genome protection.<\/p>\n<p>The dosing pen contains 500 mg of highly pure and stabilized active substance in 2 ml of solution, representing a high concentration of exactly 250 mg\/ml. Conversion for precise dosing within research protocols:<\/p>\n<p>1 ml = 100 units (IU) = 100 clicks<\/p>\n<p>0.5 ml (one full rotation of the mechanism) = 50 clicks<\/p>\n<p>Examples of research dosing:<\/p>\n<p>1 click = 2.50 mg of active substance<\/p>\n<p>2 clicks = 5.00 mg of active substance<\/p>\n<p>10 clicks (0.1 ml) = 25.00 mg of active substance<\/p>\n<p>20 clicks (0.2 ml) = 50.00 mg of active substance<\/p>\n<p>40 clicks (0.4 ml) = 100.00 mg of active substance<\/p>\n<p>50 clicks (0.5 ml \/ full rotation) = 125.00 mg of active substance<\/p>\n<p>This mechanical system ensures absolute precision, repeatability, and flexibility when setting microdoses according to the needs of a specific laboratory protocol without the need for complex manual dilution of concentrates.<\/p>\n<p><strong>Effects Studied in Research<\/strong><\/p>\n<p>In the field of metabolic and neurological research, NAD+ is studied for its ability to radically optimize mitochondrial function \u2013 the energy centers of cells. Its presence is critical for the conversion of nutrients into ATP (adenosine triphosphate), the body\u2019s primary energy currency.<\/p>\n<p>In vivo studies suggest that restoring optimal NAD+ levels activates sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3). These proteins regulate metabolic flexibility, suppress chronic intracellular inflammation, and protect cells from oxidative stress. Another important area of research is neuroprotection \u2013 scientists are studying the effect of NAD+ on cognitive function, nerve pathway regeneration, mental clarity, and the elimination of chronic fatigue at the cellular level. Its synergy with PARP enzymes, which repair breaks in DNA strands, is also being investigated.<\/p>\n<p><strong>Scientific Context and References<\/strong><\/p>\n<p>The role of NAD+ in cellular biology is among the most frequently published topics in leading academic journals such as Science and Nature, as well as in databases indexed in PubMed. Research teams worldwide confirm a direct correlation between systemic increases in the availability of this coenzyme and the extension of healthy cellular lifespan (healthspan).<\/p>\n<p>Detailed information on the impact of NAD+ supplementation on metabolic syndrome, insulin sensitivity, and muscle tissue regeneration is continuously collected in clinical proposals on ClinicalTrials.gov, where this molecule represents a fundamental pillar of modern longevity medicine and longevity research.<\/p>\n<p>The Royal Peptides dosing pen provides a modern, safe, and highly sterile solution for handling this advanced molecule under controlled laboratory conditions.<\/p>\n<p>This product is intended exclusively for scientific and research purposes. Not for direct human consumption.<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>Royal Peptides Dosing Pen \u2013 NAD+ 500mg\/2ml<\/strong><\/p>\n<p>A modern and practical dosing pen designed for precise and convenient dosing of research compounds. Its elegant design, compact construction, and simple operation enable efficient handling in laboratory environments.<\/p>\n<p>NAD+ (nicotinamide adenine dinucleotide) is an essential coenzyme present in all living cells, and it is the subject of intensive scientific research in the areas of cellular metabolism, slowing aging processes (anti-aging), DNA repair, and restoration of mitochondrial function.<\/p>\n<p>Needles are not included in the package and are not available in our product range.<\/p>\n","protected":false},"featured_media":7970,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[154,161,304,165],"product_tag":[],"class_list":["post-7971","product","type-product","status-publish","has-post-thumbnail","product_cat-anti-aging","product_cat-hormonal-balance","product_cat-accessories","product_cat-regeneration","first","instock","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>NAD+ pen 500mg - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/en\/product\/nad-pen-500mg\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NAD+ pen 500mg - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"Royal Peptides Dosing Pen \u2013 NAD+ 500mg\/2ml  A modern and practical dosing pen designed for precise and convenient dosing of research compounds. 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