{"id":3975,"date":"2026-04-22T21:07:54","date_gmt":"2026-04-22T19:07:54","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&#038;p=3975"},"modified":"2026-04-22T21:53:15","modified_gmt":"2026-04-22T19:53:15","slug":"mgf","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/hu\/produkt\/mgf","title":{"rendered":"MGF"},"content":{"rendered":"<p>MGF \u2013 kutat\u00e1si peptid (Mechano Growth Factor)<br \/>\n(Research Use Only)<\/p>\n<p>Az MGF (Mechano Growth Factor) az inzulinszer\u0171 n\u00f6veked\u00e9si faktor 1 (IGF-1) egy izoform\u00e1ja, amely a szervezet term\u00e9szetes v\u00e1laszak\u00e9nt j\u00f6n l\u00e9tre mechanikai terhel\u00e9s \u00e9s az izomsz\u00f6vet k\u00e1rosod\u00e1sa eset\u00e9n. Ez a peptid els\u0151sorban az izomregener\u00e1ci\u00f3, a sejtszaporod\u00e1s \u00e9s az adapt\u00e1ci\u00f3s folyamatok kutat\u00e1s\u00e1nak t\u00e1rgya.<\/p>\n<p>Tudom\u00e1nyos \u00e9s preklinikai vizsg\u00e1latokban az MGF-et eszk\u00f6zk\u00e9nt haszn\u00e1lj\u00e1k a lok\u00e1lis n\u00f6veked\u00e9si mechanizmusok elemz\u00e9s\u00e9re, a szatellit sejtek aktiv\u00e1l\u00e1s\u00e1ra \u00e9s az izomrostok terhel\u00e9s ut\u00e1ni helyre\u00e1ll\u00edt\u00e1s\u00e1ra.<\/p>\n<p>Mechanisztikus profil<\/p>\n<p>IGF-1 izoforma (Mechano Growth Factor)<br \/>\nAz MGF az IGF-1 alternat\u00edvan splicingolt form\u00e1ja, amely az izomsz\u00f6vet mechanikai k\u00e1rosod\u00e1s\u00e1ra adott v\u00e1laszk\u00e9nt expressz\u00e1l\u00f3dik.<\/p>\n<p>Szatellit sejtek aktiv\u00e1l\u00e1sa<br \/>\nLaborat\u00f3riumi modellekben vizsg\u00e1lj\u00e1k azt a k\u00e9pess\u00e9g\u00e9t, hogy aktiv\u00e1lja az izom szatellit sejteket, amelyek kulcsfontoss\u00e1g\u00faak az izomregener\u00e1ci\u00f3 \u00e9s n\u00f6veked\u00e9s szempontj\u00e1b\u00f3l.<\/p>\n<p>Izomregener\u00e1ci\u00f3<br \/>\nPreklinikai vizsg\u00e1latok elemzik hat\u00e1s\u00e1t a s\u00e9r\u00fclt izomrostok helyre\u00e1ll\u00edt\u00e1s\u00e1ra \u00e9s a sz\u00f6vet regener\u00e1ci\u00f3j\u00e1ra.<\/p>\n<p>\u2699 Lok\u00e1lis sejtv\u00e1lasz<br \/>\nAz MGF f\u0151k\u00e9nt lok\u00e1lisan, a s\u00e9r\u00fcl\u00e9s hely\u00e9n hat, ami lehet\u0151v\u00e9 teszi az izomsz\u00f6vet specifikus adapt\u00e1ci\u00f3s mechanizmusainak tanulm\u00e1nyoz\u00e1s\u00e1t.<\/p>\n<p>Sejtszaporod\u00e1s \u00e9s differenci\u00e1ci\u00f3<br \/>\nA kutat\u00e1s az MGF szerep\u00e9re \u00f6sszpontos\u00edt a sejtn\u00f6veked\u00e9s szab\u00e1lyoz\u00e1s\u00e1ban \u00e9s a sejtek differenci\u00e1ci\u00f3j\u00e1ban az izomsz\u00f6veten bel\u00fcl.<\/p>\n<p>El\u0151ny\u00f6k a kutat\u00e1s sz\u00e1m\u00e1ra<\/p>\n<p>Az MGF-et els\u0151sorban a k\u00f6vetkez\u0151 ter\u00fcleteken haszn\u00e1lj\u00e1k:<\/p>\n<p>izomregener\u00e1ci\u00f3 tanulm\u00e1nyoz\u00e1sa<br \/>\na szatellit sejtek aktiv\u00e1l\u00e1s\u00e1nak elemz\u00e9se<br \/>\naz IGF-1 jel\u00e1tviteli \u00fatvonalak kutat\u00e1sa<br \/>\na mechanikai terhel\u00e9shez val\u00f3 adapt\u00e1ci\u00f3s folyamatok modellez\u00e9se<br \/>\na sejtszaporod\u00e1s \u00e9s differenci\u00e1ci\u00f3 tanulm\u00e1nyoz\u00e1sa<\/p>\n<p>Kutat\u00e1si h\u00e1tt\u00e9r<\/p>\n<p>Az MGF biol\u00f3giai tulajdons\u00e1gai sz\u00e1mos tudom\u00e1nyos vizsg\u00e1lat t\u00e1rgy\u00e1t k\u00e9pezt\u00e9k:<\/p>\n<p>Goldspink G., Journal of Physiology \u2013 az MGF azonos\u00edt\u00e1sa mint mechanikusan induk\u00e1lt IGF-1 izoforma \u00e9s szerepe az izomadapt\u00e1ci\u00f3ban<br \/>\nYang SY et al., Journal of Muscle Research and Cell Motility \u2013 az MGF serkenti a szatellit sejtek aktiv\u00e1l\u00e1s\u00e1t \u00e9s t\u00e1mogatja az izomregener\u00e1ci\u00f3t<br \/>\nHill M., Goldspink G., Journal of Physiology \u2013 az izomn\u00f6veked\u00e9s szab\u00e1lyoz\u00e1sa IGF-1 izoform\u00e1kon kereszt\u00fcl<br \/>\nPhilippou A et al., Growth Hormone &#038; IGF Research \u2013 az IGF-1 \u00e9s izoform\u00e1inak szerepe a sejtszaporod\u00e1sban \u00e9s differenci\u00e1ci\u00f3ban<br \/>\nK\u00eds\u00e9rleti modellek r\u00e1mutatnak az MGF jelent\u0151s\u00e9g\u00e9re az izomsz\u00f6vet mechanikai terhel\u00e9sre adott v\u00e1lasz\u00e1ban<\/p>\n<p>Felhaszn\u00e1l\u00e1s a kutat\u00e1sban<\/p>\n<p>Az MGF-et laborat\u00f3riumi k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt els\u0151sorban a k\u00f6vetkez\u0151kre haszn\u00e1lj\u00e1k:<\/p>\n<p>izomregener\u00e1ci\u00f3 kutat\u00e1sa<br \/>\naz IGF-1\/MGF jel\u00e1tviteli \u00fatvonalak elemz\u00e9se<br \/>\na sejtszaporod\u00e1s tanulm\u00e1nyoz\u00e1sa<br \/>\naz izomsz\u00f6vet k\u00e1rosod\u00e1s\u00e1nak \u00e9s regener\u00e1ci\u00f3j\u00e1nak modellez\u00e9se<br \/>\nk\u00eds\u00e9rleti sejtes \u00e9s preklinikai vizsg\u00e1latok<\/p>\n<p>Biztons\u00e1gi \u00e9s szab\u00e1lyoz\u00e1si inform\u00e1ci\u00f3k<\/p>\n<p>Az MGF kutat\u00e1si peptidk\u00e9nt van besorolva.<\/p>\n<p>\u274c Nem enged\u00e9lyezett gy\u00f3gyszerk\u00e9nt<br \/>\n\u274c Nem alkalmas diagnosztikai c\u00e9lokra<br \/>\n\u274c Nem alkalmas hum\u00e1n vagy \u00e1llatorvosi felhaszn\u00e1l\u00e1sra<\/p>\n<p>\u2705 Kiz\u00e1r\u00f3lag laborat\u00f3riumi \u00e9s tudom\u00e1nyos kutat\u00e1sra \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d<\/p>\n<p>A term\u00e9k megv\u00e1s\u00e1rl\u00e1s\u00e1val a v\u00e1s\u00e1rl\u00f3 meger\u0151s\u00edti, hogy meg\u00e9rti annak kutat\u00e1si jelleg\u00e9t, \u00e9s v\u00e1llalja, hogy kiz\u00e1r\u00f3lag ennek megfelel\u0151en haszn\u00e1lja.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Az MGF egy kutat\u00e1si peptid \u2013 mechano growth faktor, az IGF-1 egy izoform\u00e1ja, amelyet laborat\u00f3riumi vizsg\u00e1latokban haszn\u00e1lnak az izomregener\u00e1ci\u00f3 \u00e9s a mechanikai terhel\u00e9sre adott sejtes v\u00e1lasz tanulm\u00e1nyoz\u00e1s\u00e1ra. Preklinikai kutat\u00e1sokban vizsg\u00e1lj\u00e1k hat\u00e1s\u00e1t a szatellit sejtek aktiv\u00e1l\u00e1s\u00e1ra, az izomrostok helyre\u00e1ll\u00edt\u00e1s\u00e1ra, valamint a sz\u00f6vetk\u00e1rosod\u00e1st k\u00f6vet\u0151 lok\u00e1lis adapt\u00e1ci\u00f3s folyamatokra. A term\u00e9k kiz\u00e1r\u00f3lag tudom\u00e1nyos c\u00e9lokra szolg\u00e1l.<\/p>\n","protected":false},"featured_media":3974,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[198,200,203],"product_tag":[],"class_list":{"0":"post-3975","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-aging","7":"product_cat-fitnesz","8":"product_cat-regeneracio","9":"pa_obsah-2mg","11":"first","12":"instock","13":"purchasable","14":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>MGF - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/hu\/produkt\/mgf\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MGF - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"Az MGF egy kutat\u00e1si peptid \u2013 mechano growth faktor, az IGF-1 egy izoform\u00e1ja, amelyet laborat\u00f3riumi vizsg\u00e1latokban haszn\u00e1lnak az izomregener\u00e1ci\u00f3 \u00e9s a mechanikai terhel\u00e9sre adott sejtes v\u00e1lasz tanulm\u00e1nyoz\u00e1s\u00e1ra. 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