{"id":3981,"date":"2026-04-22T21:07:54","date_gmt":"2026-04-22T19:07:54","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&#038;p=3981"},"modified":"2026-04-22T21:53:18","modified_gmt":"2026-04-22T19:53:18","slug":"peg-mgf","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/hu\/produkt\/peg-mgf","title":{"rendered":"PEG MGF"},"content":{"rendered":"<p>PEG-MGF \u2013 kutat\u00e1si peptid (pegil\u00e1lt mechano growth factor)<br \/>\n(Research Use Only)<\/p>\n<p>A PEG-MGF a mechano growth factor (MGF) szintetikus, pegil\u00e1lt form\u00e1ja, amely az inzulinszer\u0171 n\u00f6veked\u00e9si faktor 1 (IGF-1) egyik izoform\u00e1ja. A pegil\u00e1ci\u00f3 (PEG-l\u00e1nc kapcsol\u00e1sa) meghosszabb\u00edtja stabilit\u00e1s\u00e1t \u00e9s biol\u00f3giai hozz\u00e1f\u00e9rhet\u0151s\u00e9g\u00e9t k\u00eds\u00e9rleti k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt, lehet\u0151v\u00e9 t\u00e9ve hat\u00e1sainak r\u00e9szletesebb vizsg\u00e1lat\u00e1t.<\/p>\n<p>Tudom\u00e1nyos \u00e9s preklinikai vizsg\u00e1latokban a PEG-MGF-et eszk\u00f6zk\u00e9nt haszn\u00e1lj\u00e1k az izomregener\u00e1ci\u00f3, a sejtszaporod\u00e1s \u00e9s a mechanikai terhel\u00e9shez val\u00f3 alkalmazkod\u00e1si folyamatok elemz\u00e9s\u00e9re.<\/p>\n<p>Mechanisztikus profil<\/p>\n<p>IGF-1 izoforma (Mechano Growth Factor)<br \/>\nA PEG-MGF az IGF-1 egy term\u00e9szetesen el\u0151fordul\u00f3 izoform\u00e1j\u00e1b\u00f3l sz\u00e1rmazik, amely az izomsz\u00f6vet mechanikai k\u00e1rosod\u00e1s\u00e1ra adott v\u00e1laszk\u00e9nt aktiv\u00e1l\u00f3dik.<\/p>\n<p>M\u0171holdsejtek aktiv\u00e1l\u00e1sa<br \/>\nLaborat\u00f3riumi modellekben vizsg\u00e1lj\u00e1k azon k\u00e9pess\u00e9g\u00e9t, hogy aktiv\u00e1lja az izom m\u0171holdsejtjeit, amelyek kulcsszerepet j\u00e1tszanak az izomregener\u00e1ci\u00f3ban.<\/p>\n<p>Izomregener\u00e1ci\u00f3<br \/>\nPreklinikai vizsg\u00e1latok elemzik hat\u00e1s\u00e1t a s\u00e9r\u00fclt izomrostok helyre\u00e1ll\u00edt\u00e1s\u00e1ra \u00e9s a sz\u00f6vetek regener\u00e1ci\u00f3j\u00e1ra.<\/p>\n<p>\u2699 Meghosszabb\u00edtott biol\u00f3giai aktivit\u00e1s<br \/>\nA pegil\u00e1ci\u00f3 lehet\u0151v\u00e9 teszi a molekula hosszabb ideig tart\u00f3 hat\u00e1s\u00e1t k\u00eds\u00e9rleti k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt, ami b\u0151v\u00edti az id\u0151f\u00fcgg\u0151 hat\u00e1sok kutat\u00e1s\u00e1nak lehet\u0151s\u00e9geit.<\/p>\n<p>Sejtszaporod\u00e1s \u00e9s differenci\u00e1ci\u00f3<br \/>\nA kutat\u00e1s a sejtn\u00f6veked\u00e9s szab\u00e1lyoz\u00e1s\u00e1ban \u00e9s azok izomsz\u00f6vetben t\u00f6rt\u00e9n\u0151 differenci\u00e1l\u00f3d\u00e1s\u00e1ban bet\u00f6lt\u00f6tt szerep\u00e9re \u00f6sszpontos\u00edt.<\/p>\n<p>El\u0151ny\u00f6k a kutat\u00e1sban<\/p>\n<p>A PEG-MGF-et f\u0151k\u00e9nt az al\u00e1bbi ter\u00fcleteken alkalmazz\u00e1k:<\/p>\n<p>izomregener\u00e1ci\u00f3 vizsg\u00e1lata<br \/>\nm\u0171holdsejtek aktiv\u00e1ci\u00f3j\u00e1nak elemz\u00e9se<br \/>\nIGF-1 jel\u00e1tviteli \u00fatvonalak kutat\u00e1sa<br \/>\nmechanikai terhel\u00e9shez val\u00f3 alkalmazkod\u00e1si folyamatok modellez\u00e9se<br \/>\nsejtszaporod\u00e1s \u00e9s differenci\u00e1ci\u00f3 vizsg\u00e1lata<\/p>\n<p>Kutat\u00e1si h\u00e1tt\u00e9r<\/p>\n<p>Az MGF \u00e9s sz\u00e1rmaz\u00e9kainak biol\u00f3giai tulajdons\u00e1gai t\u00f6bb tudom\u00e1nyos vizsg\u00e1lat t\u00e1rgy\u00e1t k\u00e9pezt\u00e9k:<\/p>\n<p>Goldspink G., Journal of Physiology \u2013 az MGF azonos\u00edt\u00e1sa mint mechanikailag induk\u00e1lt IGF-1 izoforma \u00e9s szerepe az izomadapt\u00e1ci\u00f3ban<br \/>\nYang SY et al., Journal of Muscle Research and Cell Motility \u2013 az MGF serkenti a m\u0171holdsejtek aktiv\u00e1ci\u00f3j\u00e1t \u00e9s az izomregener\u00e1ci\u00f3t<br \/>\nPhilippou A et al., Growth Hormone &#038; IGF Research \u2013 az IGF-1 izoform\u00e1k szerepe az izomn\u00f6veked\u00e9s \u00e9s a sz\u00f6vetregener\u00e1ci\u00f3 szab\u00e1lyoz\u00e1s\u00e1ban<br \/>\nHill M., Goldspink G., Journal of Physiology \u2013 az izomn\u00f6veked\u00e9s szab\u00e1lyoz\u00e1s\u00e1nak mechanizmusai IGF-1 \u00e9s MGF r\u00e9v\u00e9n<br \/>\nK\u00eds\u00e9rleti vizsg\u00e1latok arra utalnak, hogy a pegil\u00e1lt peptidek meghosszabb\u00edthatj\u00e1k a biol\u00f3giai aktivit\u00e1st \u00e9s stabilit\u00e1st laborat\u00f3riumi k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt<\/p>\n<p>Felhaszn\u00e1l\u00e1s a kutat\u00e1sban<\/p>\n<p>A PEG-MGF-et laborat\u00f3riumi k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt f\u0151k\u00e9nt az al\u00e1bbiakra haszn\u00e1lj\u00e1k:<\/p>\n<p>izomregener\u00e1ci\u00f3 kutat\u00e1sa<br \/>\nIGF-1\/MGF jel\u00e1tviteli \u00fatvonalak elemz\u00e9se<br \/>\nsejtszaporod\u00e1s vizsg\u00e1lata<br \/>\naz izomsz\u00f6vet k\u00e1rosod\u00e1s\u00e1nak \u00e9s helyre\u00e1ll\u00edt\u00e1s\u00e1nak modellez\u00e9se<br \/>\nk\u00eds\u00e9rleti sejtes \u00e9s preklinikai vizsg\u00e1latok<\/p>\n<p>Biztons\u00e1gi \u00e9s szab\u00e1lyoz\u00e1si inform\u00e1ci\u00f3k<\/p>\n<p>A PEG-MGF kutat\u00e1si peptidk\u00e9nt van besorolva.<\/p>\n<p>\u274c Nem enged\u00e9lyezett gy\u00f3gyszerk\u00e9nt<br \/>\n\u274c Nem alkalmas diagnosztikai c\u00e9lokra<br \/>\n\u274c Nem \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d emberi vagy \u00e1llatgy\u00f3gy\u00e1szati felhaszn\u00e1l\u00e1sra<\/p>\n<p>\u2705 Kiz\u00e1r\u00f3lag laborat\u00f3riumi \u00e9s tudom\u00e1nyos kutat\u00e1sra \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d<\/p>\n<p>A term\u00e9k megv\u00e1s\u00e1rl\u00e1s\u00e1val a v\u00e1s\u00e1rl\u00f3 meger\u0151s\u00edti, hogy tiszt\u00e1ban van annak kutat\u00e1si jelleg\u00e9vel, \u00e9s v\u00e1llalja, hogy kiz\u00e1r\u00f3lag ennek megfelel\u0151en haszn\u00e1lja.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A PEG-MGF egy kutat\u00e1si peptid \u2013 a mechano growth factor (MGF) pegil\u00e1lt form\u00e1ja, amelyet izomregener\u00e1ci\u00f3ra \u00e9s sejtszaporod\u00e1sra ir\u00e1nyul\u00f3 laborat\u00f3riumi vizsg\u00e1latokban alkalmaznak. Preklinikai kutat\u00e1sokban vizsg\u00e1lj\u00e1k a m\u0171holdsejtek aktiv\u00e1l\u00e1s\u00e1ra, az izomrostok helyre\u00e1ll\u00edt\u00e1s\u00e1ra, valamint a mechanikai terhel\u00e9shez val\u00f3 alkalmazkod\u00e1ssal \u00f6sszef\u00fcgg\u0151 folyamatokra gyakorolt hat\u00e1s\u00e1t. A term\u00e9k kiz\u00e1r\u00f3lag tudom\u00e1nyos c\u00e9lokra k\u00e9sz\u00fclt.<\/p>\n","protected":false},"featured_media":3980,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[198,200,203],"product_tag":[],"class_list":{"0":"post-3981","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-aging","7":"product_cat-fitnesz","8":"product_cat-regeneracio","9":"pa_obsah-2mg","11":"first","12":"instock","13":"purchasable","14":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>PEG MGF - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/hu\/produkt\/peg-mgf\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PEG MGF - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"A PEG-MGF egy kutat\u00e1si peptid \u2013 a mechano growth factor (MGF) pegil\u00e1lt form\u00e1ja, amelyet izomregener\u00e1ci\u00f3ra \u00e9s sejtszaporod\u00e1sra ir\u00e1nyul\u00f3 laborat\u00f3riumi vizsg\u00e1latokban alkalmaznak. 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