{"id":3066,"date":"2026-03-04T10:57:09","date_gmt":"2026-03-04T09:57:09","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&p=3066"},"modified":"2026-04-16T00:03:05","modified_gmt":"2026-04-15T22:03:05","slug":"aicar","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar","title":{"rendered":"Aicar"},"content":{"rendered":"

AICAR \u2013 peptide de cercetare<\/p>\n

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) este un analog sintetic de nucleotid, utilizat \u00een cercetare, \u00een studii experimentale \u0219i preclinice, pentru activarea AMP-activated protein kinase (AMPK) \u2013 regulator central al echilibrului energetic celular. Acest peptid reprezint\u0103 un instrument esen\u021bial pentru studiul metabolismului, adapt\u0103rii celulare la stres energetic \u0219i mecanismelor anti-aging.<\/p>\n

AICAR este utilizat \u00een modele de laborator pentru simularea deficitului energetic celular \u0219i pentru studiul plasticit\u0103\u021bii metabolice.<\/p>\n

De ce este AICAR obiect de cercetare
\nAICAR permite oamenilor de \u0219tiin\u021b\u0103 s\u0103 analizeze mai multe procese biologice fundamentale:<\/p>\n

Activarea c\u0103ii de semnalizare AMPK<\/p>\n

Reglarea metabolismului energetic celular<\/p>\n

Studiul activit\u0103\u021bii mitocondriale<\/p>\n

Cercetarea adapt\u0103rii metabolice a celulelor<\/p>\n

Modelarea mecanismelor anti-aging<\/p>\n

Mecanism de ac\u021biune (context de cercetare)
\n\u00cen condi\u021bii experimentale, AICAR ac\u021bioneaz\u0103 ca activator intracelular al AMPK, simul\u00e2nd o stare de disponibilitate energetic\u0103 sc\u0103zut\u0103. Activarea AMPK determin\u0103 reglarea c\u0103ilor metabolice responsabile de producerea energiei, regenerarea celular\u0103, autofagie \u0219i adaptarea celulelor la condi\u021bii de stres.<\/p>\n

Cercet\u0103torii utilizeaz\u0103 AICAR \u00een culturi celulare \u0219i modele preclinice pentru a analiza echilibrul metabolic, regenerarea celular\u0103 \u0219i procesele asociate \u00eemb\u0103tr\u00e2nirii celulare.<\/p>\n

Domenii de utilizare \u00een cercetare
\nAICAR este utilizat \u00een principal \u00een:<\/p>\n

Cercetarea metabolic\u0103<\/p>\n

Studiul energiei celulare<\/p>\n

Cercetarea anti-aging<\/p>\n

Biologia mitocondrial\u0103<\/p>\n

Semnalizarea molecular\u0103<\/p>\n

Baz\u0103 \u0219tiin\u021bific\u0103 \u0219i surse
\nUtilizarea AICAR este sus\u021binut\u0103 de numeroase studii publicate:<\/p>\n

1\ufe0f\u20e3 Narkar V.A. et al.
\nAMPK activation enhances endurance and metabolic gene expression in skeletal muscle,
\nCell Metabolism, 2008
\n\u2192 Studiu preclinic care demonstreaz\u0103 rolul AICAR \u00een activarea AMPK \u0219i reglarea c\u0103ilor metabolice implicate \u00een adaptarea energetic\u0103 a celulelor.<\/p>\n

2\ufe0f\u20e3 Hardie D.G. et al.
\nAMPK: a key regulator of energy balance in cells,
\nNature Reviews Molecular Cell Biology, 2012
\n\u2192 Articol de sintez\u0103 care descrie mecanismele activ\u0103rii AMPK \u0219i rolul s\u0103u \u00een metabolism, regenerare celular\u0103 \u0219i \u00eemb\u0103tr\u00e2nire.<\/p>\n

3\ufe0f\u20e3 L\u00f3pez-Ot\u00edn C. et al.
\nThe Hallmarks of Aging,
\nCell, 2013
\n\u2192 Studiu care identific\u0103 dereglarea metabolic\u0103 \u0219i disfunc\u021bia mitocondrial\u0103 ca factori cheie ai \u00eemb\u0103tr\u00e2nirii biologice, \u021binte ale modula\u021biei AMPK.<\/p>\n

4\ufe0f\u20e3 Modele preclinice (in vitro \/ in vivo)
\nStudii experimentale care analizeaz\u0103 efectul AICAR asupra metabolismului celular, autofagiei, echilibrului energetic \u0219i adapt\u0103rii la stres.<\/p>\n

Informa\u021bii de siguran\u021b\u0103 \u0219i reglementare
\n\u26a0\ufe0f Aten\u021bionare important\u0103:<\/p>\n

AICAR este destinat exclusiv utiliz\u0103rii \u00een laborator \u0219i cercet\u0103rii \u0219tiin\u021bifice<\/p>\n

Nu este aprobat ca medicament<\/p>\n

Nu este destinat utiliz\u0103rii la oameni sau animale<\/p>\n

Nu este destinat consumului sau aplica\u021biilor clinice<\/p>\n

Produsul este distribuit exclusiv institu\u021biilor de cercetare, laboratoarelor \u0219i utiliz\u0103rii experimentale profesionale.<\/p>\n","protected":false},"excerpt":{"rendered":"

AICAR este un peptid de cercetare utilizat \u00een modele de laborator pentru studiul energiei celulare, activ\u0103rii c\u0103ii AMPK \u0219i mecanismelor asociate metabolismului \u0219i \u00eemb\u0103tr\u00e2nirii celulare.<\/p>\n

\u2705 Doar pentru scopuri de cercetare
\n\u274c Nu este destinat utiliz\u0103rii la om<\/p>\n

Con\u021binut:<\/strong> 50mg<\/p>\n","protected":false},"featured_media":3065,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[250,248],"product_tag":[],"class_list":["post-3066","product","type-product","status-publish","has-post-thumbnail","product_cat-anti-aging","product_cat-regenerare","pa_dolezite-upozornenie-vsetky-produkty-dostupne-v-nasej-ponuke-su-urcene-vyhradne-na-vyskumne-laboratorne-a-vyvojove-ucely-nie-su-urcene-na-pouzitie-ako-liek-zdravotnicka-pomocka-kozmeticky-pripra","pa_obsah-50mg","first","instock","purchasable","product-type-simple"],"yoast_head":"\nAicar - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Aicar - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"AICAR este un peptid de cercetare utilizat \u00een modele de laborator pentru studiul energiei celulare, activ\u0103rii c\u0103ii AMPK \u0219i mecanismelor asociate metabolismului \u0219i \u00eemb\u0103tr\u00e2nirii celulare. \u2705 Doar pentru scopuri de cercetare \u274c Nu este destinat utiliz\u0103rii la om Con\u021binut: 50mg\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar\" \/>\n<meta property=\"og:site_name\" content=\"Royal Peptides\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/profile.php?id=61588101646707\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-15T22:03:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/02\/AICAR-50mg.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1536\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Timp estimat pentru citire\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar\",\"url\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar\",\"name\":\"Aicar - Royal Peptides\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.royalpeptides.eu\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/AICAR-50mg.png\",\"datePublished\":\"2026-03-04T09:57:09+00:00\",\"dateModified\":\"2026-04-15T22:03:05+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar#breadcrumb\"},\"inLanguage\":\"ro-RO\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ro-RO\",\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar#primaryimage\",\"url\":\"https:\\\/\\\/www.royalpeptides.eu\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/AICAR-50mg.png\",\"contentUrl\":\"https:\\\/\\\/www.royalpeptides.eu\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/AICAR-50mg.png\",\"width\":1024,\"height\":1536},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/produkt\\\/aicar#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Domovsk\u00e1 str\u00e1nka\",\"item\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cump\u0103r\u0103 peptide\",\"item\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\\\/cumpara-peptide\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Aicar\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro#website\",\"url\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\",\"name\":\"Royal Peptides\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ro-RO\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro#organization\",\"name\":\"Royal Peptides\",\"url\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ro-RO\",\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.royalpeptides.eu\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/royal_peptides_fade_edges.png\",\"contentUrl\":\"https:\\\/\\\/www.royalpeptides.eu\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/royal_peptides_fade_edges.png\",\"width\":2048,\"height\":909,\"caption\":\"Royal Peptides\"},\"image\":{\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/ro#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/profile.php?id=61588101646707\",\"https:\\\/\\\/www.instagram.com\\\/royal_pep?igsh=Z2RoamNlaW1sZmFr\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Aicar - Royal Peptides","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar","og_locale":"ro_RO","og_type":"article","og_title":"Aicar - Royal Peptides","og_description":"AICAR este un peptid de cercetare utilizat \u00een modele de laborator pentru studiul energiei celulare, activ\u0103rii c\u0103ii AMPK \u0219i mecanismelor asociate metabolismului \u0219i \u00eemb\u0103tr\u00e2nirii celulare. \u2705 Doar pentru scopuri de cercetare \u274c Nu este destinat utiliz\u0103rii la om Con\u021binut: 50mg","og_url":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar","og_site_name":"Royal Peptides","article_publisher":"https:\/\/www.facebook.com\/profile.php?id=61588101646707","article_modified_time":"2026-04-15T22:03:05+00:00","og_image":[{"width":1024,"height":1536,"url":"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/02\/AICAR-50mg.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_misc":{"Timp estimat pentru citire":"3 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar","url":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar","name":"Aicar - Royal Peptides","isPartOf":{"@id":"https:\/\/www.royalpeptides.eu\/ro#website"},"primaryImageOfPage":{"@id":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar#primaryimage"},"image":{"@id":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar#primaryimage"},"thumbnailUrl":"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/02\/AICAR-50mg.png","datePublished":"2026-03-04T09:57:09+00:00","dateModified":"2026-04-15T22:03:05+00:00","breadcrumb":{"@id":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar#breadcrumb"},"inLanguage":"ro-RO","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar"]}]},{"@type":"ImageObject","inLanguage":"ro-RO","@id":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar#primaryimage","url":"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/02\/AICAR-50mg.png","contentUrl":"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/02\/AICAR-50mg.png","width":1024,"height":1536},{"@type":"BreadcrumbList","@id":"https:\/\/www.royalpeptides.eu\/ro\/produkt\/aicar#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Domovsk\u00e1 str\u00e1nka","item":"https:\/\/www.royalpeptides.eu\/ro"},{"@type":"ListItem","position":2,"name":"Cump\u0103r\u0103 peptide","item":"https:\/\/www.royalpeptides.eu\/ro\/cumpara-peptide"},{"@type":"ListItem","position":3,"name":"Aicar"}]},{"@type":"WebSite","@id":"https:\/\/www.royalpeptides.eu\/ro#website","url":"https:\/\/www.royalpeptides.eu\/ro","name":"Royal Peptides","description":"","publisher":{"@id":"https:\/\/www.royalpeptides.eu\/ro#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.royalpeptides.eu\/ro?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ro-RO"},{"@type":"Organization","@id":"https:\/\/www.royalpeptides.eu\/ro#organization","name":"Royal Peptides","url":"https:\/\/www.royalpeptides.eu\/ro","logo":{"@type":"ImageObject","inLanguage":"ro-RO","@id":"https:\/\/www.royalpeptides.eu\/ro#\/schema\/logo\/image\/","url":"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/02\/royal_peptides_fade_edges.png","contentUrl":"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/02\/royal_peptides_fade_edges.png","width":2048,"height":909,"caption":"Royal Peptides"},"image":{"@id":"https:\/\/www.royalpeptides.eu\/ro#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/profile.php?id=61588101646707","https:\/\/www.instagram.com\/royal_pep?igsh=Z2RoamNlaW1sZmFr"]}]}},"_links":{"self":[{"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/product\/3066","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/comments?post=3066"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/media\/3065"}],"wp:attachment":[{"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/media?parent=3066"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/product_brand?post=3066"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/product_cat?post=3066"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.royalpeptides.eu\/ro\/wp-json\/wp\/v2\/product_tag?post=3066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}