{"id":7786,"date":"2026-06-16T21:55:12","date_gmt":"2026-06-16T19:55:12","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&p=7786"},"modified":"2026-07-21T19:45:41","modified_gmt":"2026-07-21T17:45:41","slug":"ss-31-pen-50mg","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/sl\/produkt\/ss-31-pen-50mg","title":{"rendered":"SS-31 pen 50mg"},"content":{"rendered":"

SS-31 \u2013 Dozirni injekcijski peresnik 50mg\/2ml (Mitochondria-Targeting Antioxidant Peptide \/ Elamipretide)<\/strong><\/p>\n

SS-31 (kemijsko D-Arg-Dmt-Lys-Phe-NH2, znan tudi pod imenoma Elamipretide ali Bendavia) predstavlja popolnoma nov razred majhnih eksperimentalnih peptidov, ki so usmerjeni neposredno v mitohondrije. Za razliko od standardnih antioksidantov, ki ne morejo u\u010dinkovito prehajati skozi celi\u010dne pregrade, SS-31 zaradi svojega specifi\u010dnega naboja deluje neposredno na notranjo mitohondrijsko membrano. V sodobnih biomedicinskih raziskavah in na podro\u010dju longevity ta molekula velja za prelomno, saj ciljno obravnava mitohondrijsko disfunkcijo \u2013 enega glavnih spro\u017eilcev celi\u010dnega staranja, degenerativnih bolezni in energijske iz\u010drpanosti celic.<\/p>\n

Dozirni injekcijski peresnik vsebuje 50 mg visoko pre\u010di\u0161\u010dene in stabilizirane u\u010dinkovine v 2 ml raztopine, kar predstavlja koncentracijo natanko 25 mg\/ml. Prera\u010dun za natan\u010dno odmerjanje v okviru raziskovalnih protokolov:<\/p>\n

1 ml = 100 enot (UI) = 100 klikov<\/p>\n

0,5 ml (en polni obrat mehanizma) = 50 klikov<\/p>\n

Primeri odmerjanja za raziskovalne namene:<\/p>\n

1 klik = 0,25 mg u\u010dinkovine<\/p>\n

2 klika = 0,50 mg u\u010dinkovine<\/p>\n

4 kliki = 1,00 mg u\u010dinkovine<\/p>\n

10 klikov (0,1 ml) = 2,50 mg u\u010dinkovine<\/p>\n

20 klikov (0,2 ml) = 5,00 mg u\u010dinkovine<\/p>\n

40 klikov (0,4 ml) = 10,00 mg u\u010dinkovine<\/p>\n

Ta mehanski sistem zagotavlja popolno natan\u010dnost, ponovljivost in prilagodljivost pri nastavljanju mikroodmerkov glede na zahteve posameznega laboratorijskega protokola, brez potrebe po zapletenem in napakam izpostavljenem ro\u010dnem red\u010denju.<\/p>\n

U\u010dinki, ki jih raziskuje znanost<\/strong><\/p>\n

Primarni in najpomembnej\u0161i mehanizem delovanja SS-31, ki ga znanstveniki podrobno raziskujejo, je njegova selektivna vezava na kardiolipin \u2013 edinstven fosfolipid, ki se nahaja izklju\u010dno v notranji mitohondrijski membrani. Kardiolipin sidra proteinske komplekse dihalne verige, odgovorne za proizvodnjo energije. Med oksidativnim stresom se kardiolipin po\u0161koduje, kar povzro\u010di poru\u0161itev strukture membrane in spro\u0161\u010danje reaktivnih kisikovih zvrsti (ROS). Dokazano je, da SS-31 stabilizira kardiolipin in tako neposredno obnavlja arhitekturo notranje membrane (kriste).<\/p>\n

Ta proces vodi do takoj\u0161nje optimizacije proizvodnje ATP (celi\u010dne energije) in drasti\u010dnega zmanj\u0161anja nastajanja \u0161kodljivih reaktivnih kisikovih zvrsti neposredno na njihovem izvoru. V \u0161tudijah in vivo je SS-31 pokazal izjemen potencial pri za\u0161\u010diti pred ishemi\u010dno-reperfuzijsko po\u0161kodbo (na primer pri miokardnem infarktu ali akutni po\u0161kodbi ledvic), kjer hitro prepre\u010duje celi\u010dno smrt (apoptozo). Zelo obetavne raziskave potekajo tudi na podro\u010dju nevrodegenerativnih bolezni (kot so Alzheimerjeva bolezen, Parkinsonova bolezen in s starostjo povezano kognitivno upadanje), mi\u0161i\u010dne atrofije in kroni\u010dne utrujenosti, kjer obnova mitohondrijskega zdravja ka\u017ee pomembno izbolj\u0161anje motori\u010dnih in kognitivnih funkcij preiskovancev.<\/p>\n

Znanstveni kontekst in viri<\/strong><\/p>\n

Molekula SS-31 je bila obse\u017eno preizku\u0161ena v naprednih klini\u010dnih in predklini\u010dnih \u0161tudijah, usmerjenih v presnovne, kardiolo\u0161ke in mitohondrijske patologije. Na stotine strokovnih, recenziranih znanstvenih del, ki podrobno opisujejo njeno interakcijo z bioenergetskimi potmi celice, je prosto dostopnih v ugledni mednarodni podatkovni zbirki PubMed.<\/p>\n

Natan\u010dne informacije o farmakokinetiki, vplivu elamipretida na delovanje skeletnih mi\u0161ic, zmanj\u0161evanju znotrajceli\u010dnega vnetja in za\u0161\u010diti \u017eilnega endotelija se sproti zbirajo v akademskih registrih na ClinicalTrials.gov, kjer ta snov predstavlja klju\u010dni model za razvoj prihodnjih naprednih terapij, ki temeljijo na mitohondrijski medicini.<\/p>\n

Dozirni injekcijski peresnik Royal Peptides zagotavlja sodobno, varno in visoko sterilno re\u0161itev za rokovanje s to napredno molekulo v nadzorovanih laboratorijskih pogojih.<\/p>\n

Izdelek je namenjen izklju\u010dno znanstvenim in raziskovalnim namenom. Ni namenjen neposredni uporabi ali u\u017eivanju.<\/p>\n","protected":false},"excerpt":{"rendered":"

Dozirni injekcijski peresnik Royal Peptides \u2013 SS-31 50mg\/2ml<\/strong> Sodoben in prakti\u010den dozirni injekcijski peresnik, zasnovan za natan\u010dno in priro\u010dno odmerjanje raziskovalnih spojin. Eleganten dizajn, kompaktna izvedba in enostavno upravljanje omogo\u010dajo u\u010dinkovito uporabo v laboratorijskem okolju. SS-31 (Elamipretide) je inovativen sinteti\u010dni tetrapeptid, usmerjen neposredno v mitohondrije, ki izkazuje izjemno mo\u010dne citoprotektivne in antioksidativne lastnosti. Je predmet intenzivnih znanstvenih raziskav na podro\u010dju obnove delovanja mitohondrijskih membran, radikalnega zmanj\u0161anja znotrajceli\u010dnega oksidativnega stresa, optimizacije proizvodnje energije ATP in za\u0161\u010dite organov pred ishemi\u010dno-reperfuzijsko po\u0161kodbo. Igle niso prilo\u017eene pakiranju in niso del na\u0161e ponudbe. Izdelek je namenjen izklju\u010dno znanstvenim in raziskovalnim namenom.<\/p>\n","protected":false},"featured_media":7785,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[333,336,323],"product_tag":[],"class_list":["post-7786","product","type-product","status-publish","has-post-thumbnail","product_cat-fitnes","product_cat-hormonsko-ravnovesje","product_cat-peresa","first","instock","purchasable","product-type-simple"],"yoast_head":"\nSS-31 pen 50mg - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/sl\/produkt\/ss-31-pen-50mg\" \/>\n<meta property=\"og:locale\" content=\"sl_SI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SS-31 pen 50mg - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"Dozirni injekcijski peresnik Royal Peptides \u2013 SS-31 50mg\/2ml Sodoben in prakti\u010den dozirni injekcijski peresnik, zasnovan za natan\u010dno in priro\u010dno odmerjanje raziskovalnih spojin. Eleganten dizajn, kompaktna izvedba in enostavno upravljanje omogo\u010dajo u\u010dinkovito uporabo v laboratorijskem okolju. SS-31 (Elamipretide) je inovativen sinteti\u010dni tetrapeptid, usmerjen neposredno v mitohondrije, ki izkazuje izjemno mo\u010dne citoprotektivne in antioksidativne lastnosti. Je predmet intenzivnih znanstvenih raziskav na podro\u010dju obnove delovanja mitohondrijskih membran, radikalnega zmanj\u0161anja znotrajceli\u010dnega oksidativnega stresa, optimizacije proizvodnje energije ATP in za\u0161\u010dite organov pred ishemi\u010dno-reperfuzijsko po\u0161kodbo. Igle niso prilo\u017eene pakiranju in niso del na\u0161e ponudbe. 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