{"id":7788,"date":"2026-06-16T21:55:12","date_gmt":"2026-06-16T19:55:12","guid":{"rendered":"https:\/\/www.royalpeptides.eu\/?post_type=product&p=7788"},"modified":"2026-06-19T14:33:24","modified_gmt":"2026-06-19T12:33:24","slug":"epithalon-pen-50mg","status":"publish","type":"product","link":"https:\/\/www.royalpeptides.eu\/sl\/produkt\/epithalon-pen-50mg","title":{"rendered":"Epithalon pen 50mg"},"content":{"rendered":"

Epithalon \u2013 Dozirni injekcijski peresnik 50mg\/2ml (Telomerase Activator & Anti-Aging Peptide)<\/strong><\/p>\n

Epithalon (znan tudi kot Epitalon ali peptid AEDG) je visoko pre\u010di\u0161\u010dena sinteti\u010dna replika naravnega peptida epitalamina, ki ga proizvaja epifiza (\u010de\u0161arika). Ta edinstvena molekula je bila odkrita in podrobno raziskana na In\u0161titutu za bioregulacijo in gerontologijo v Sankt Peterburgu pod vodstvom profesorja Vladimirja Khavinsona. V sodobnih gerontolo\u0161kih raziskavah predstavlja Epithalon enega temeljnih stebrov. Raziskujejo ga zaradi njegove edinstvene sposobnosti, da prodre neposredno v celi\u010dno jedro in sodeluje z DNK, kar vodi do ponovnega zagona popravljalnih mehanizmov, ki z napredovanjem starosti naravno upadajo.<\/p>\n

Dozirni injekcijski peresnik vsebuje 50 mg stabilizirane u\u010dinkovine v 2 ml raztopine, kar predstavlja koncentracijo natanko 25 mg\/ml. Prera\u010dun za natan\u010dno odmerjanje v okviru raziskovalnih protokolov:<\/p>\n

1 ml = 100 enot (UI) = 100 klikov<\/p>\n

0,5 ml (en polni obrat mehanizma) = 50 klikov<\/p>\n

Primeri odmerjanja za raziskovalne namene:<\/p>\n

1 klik = 0,25 mg u\u010dinkovine<\/p>\n

2 klika = 0,50 mg u\u010dinkovine<\/p>\n

4 kliki = 1,00 mg u\u010dinkovine<\/p>\n

10 klikov (0,1 ml) = 2,50 mg u\u010dinkovine<\/p>\n

20 klikov (0,2 ml) = 5,00 mg u\u010dinkovine<\/p>\n

40 klikov (0,4 ml) = 10,00 mg u\u010dinkovine<\/p>\n

Ta mehanski sistem zagotavlja popolno natan\u010dnost, ponovljivost in prilagodljivost pri nastavljanju mikroodmerkov glede na potrebe posameznega laboratorijskega protokola brez potrebe po zapletenem ro\u010dnem red\u010denju.<\/p>\n

U\u010dinki, ki jih preu\u010dujejo raziskave<\/strong><\/p>\n

Najpomembnej\u0161i in najpogosteje prou\u010devani mehanizem delovanja Epithalona je aktivacija telomeraze. Pri vsaki delitvi celice se kon\u010dni deli kromosomov \u2013 telomeri \u2013 nekoliko skraj\u0161ajo. Ko dose\u017eejo kriti\u010dno dol\u017eino (t. i. Hayflickova meja), celica izgubi sposobnost delitve, se stara in odmre. Raziskovalni podatki in vitro in in vivo potrjujejo, da lahko Epithalon ponovno aktivira encim telomerazo, ki telomere znova podalj\u0161a. Na ta na\u010din u\u010dinkovito premakne celi\u010dno mejo delitve, kar vodi do ob\u010dutnega podalj\u0161anja zdravega \u017eivljenjskega cikla celic (healthspan) in njihove pomladitve.<\/p>\n

Drugo klju\u010dno podro\u010dje raziskav je normalizacija delovanja epifize. Epithalon spodbuja nastajanje endogenega melatonina in obnavlja poru\u0161en cirkadiani ritem (izmenjavanje budnosti in spanja), ki je pri starajo\u010dih se ali stresnih modelih pogosto moten. Poleg tega \u0161tudije spremljajo njegovo sposobnost zmanj\u0161evanja oksidativnega stresa (deluje kot mo\u010dan lovilec prostih radikalov), uravnavanja ravni hormonov v nevroendokrinem sistemu, izbolj\u0161anja ob\u010dutljivosti na inzulin ter krepitve imunskega sistema s stimulacijo T-limfocitov. Raziskave se osredoto\u010dajo tudi na njegov potencial za zmanj\u0161anje pogostosti spontanih tumorskih mutacij v starajo\u010dih se tkivih.<\/p>\n

Znanstveni kontekst in viri<\/strong><\/p>\n

Zaradi ve\u010d kot tridesetletnih klini\u010dnih in laboratorijskih raziskav na obmo\u010dju nekdanje Sovjetske zveze in pozneje po vsem svetu velja Epithalon za eno najvarnej\u0161ih in najbolje raziskanih molekul na podro\u010dju dolgo\u017eivosti. Na desetine recenziranih \u0161tudij, ki potrjujejo podalj\u0161anje povpre\u010dne \u017eivljenjske dobe pri preu\u010devanih modelih, je prosto dostopnih v mednarodni medicinski podatkovni zbirki PubMed.<\/p>\n

Natan\u010dne informacije o epigenetskih mehanizmih tega kratkega peptida in njegovem vplivu na sintezo beljakovin, ki uravnavajo staranje, se sproti spremljajo v akademskih raziskovalnih projektih na ClinicalTrials.gov, kjer ta snov predstavlja osnovni model za raziskovanje obrata biolo\u0161ke starosti organizma.<\/p>\n

Dozirni injekcijski peresnik Royal Peptides zagotavlja sodobno, varno in visoko sterilno re\u0161itev za delo s to napredno molekulo v nadzorovanih laboratorijskih pogojih.<\/p>\n

Izdelek je namenjen izklju\u010dno za znanstvene in raziskovalne namene. Ni namenjen neposredni uporabi pri ljudeh.<\/p>\n","protected":false},"excerpt":{"rendered":"

Dozirni injekcijski peresnik Royal Peptides \u2013 Epithalon 50mg\/2ml<\/strong><\/p>\n

Sodoben in prakti\u010den dozirni injekcijski peresnik, zasnovan za natan\u010dno in priro\u010dno odmerjanje raziskovalnih spojin. Eleganten dizajn, kompaktna izvedba in enostavno upravljanje omogo\u010dajo u\u010dinkovito uporabo v laboratorijskem okolju.<\/p>\n

Epithalon (Epitalon) je sinteti\u010dni tetrapeptid, sestavljen iz \u0161tirih aminokislin (Ala-Glu-Asp-Gly). V biomedicinskih raziskavah predstavlja eno najpomembnej\u0161ih molekul na podro\u010dju dolgo\u017eivosti in anti-aginga. Predmet intenzivnega znanstvenega zanimanja je zaradi svojega potenciala za spodbujanje aktivnosti encima telomeraze, podalj\u0161anje \u017eivljenjskega cikla celic, optimizacijo endokrine funkcije epifize in uravnavanje izlo\u010danja naravnega melatonina.<\/p>\n

Igle niso prilo\u017eene pakiranju in niso del na\u0161e ponudbe.<\/p>\n

Izdelek je namenjen izklju\u010dno za znanstvene in raziskovalne namene.<\/p>\n","protected":false},"featured_media":7787,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[323,328,344],"product_tag":[],"class_list":["post-7788","product","type-product","status-publish","has-post-thumbnail","product_cat-peresa","product_cat-proti-staranju","product_cat-regeneracija","first","instock","purchasable","product-type-simple"],"yoast_head":"\nEpithalon pen 50mg - Royal Peptides<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.royalpeptides.eu\/sl\/produkt\/epithalon-pen-50mg\" \/>\n<meta property=\"og:locale\" content=\"sl_SI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Epithalon pen 50mg - Royal Peptides\" \/>\n<meta property=\"og:description\" content=\"Dozirni injekcijski peresnik Royal Peptides \u2013 Epithalon 50mg\/2ml Sodoben in prakti\u010den dozirni injekcijski peresnik, zasnovan za natan\u010dno in priro\u010dno odmerjanje raziskovalnih spojin. Eleganten dizajn, kompaktna izvedba in enostavno upravljanje omogo\u010dajo u\u010dinkovito uporabo v laboratorijskem okolju. Epithalon (Epitalon) je sinteti\u010dni tetrapeptid, sestavljen iz \u0161tirih aminokislin (Ala-Glu-Asp-Gly). V biomedicinskih raziskavah predstavlja eno najpomembnej\u0161ih molekul na podro\u010dju dolgo\u017eivosti in anti-aginga. Predmet intenzivnega znanstvenega zanimanja je zaradi svojega potenciala za spodbujanje aktivnosti encima telomeraze, podalj\u0161anje \u017eivljenjskega cikla celic, optimizacijo endokrine funkcije epifize in uravnavanje izlo\u010danja naravnega melatonina. Igle niso prilo\u017eene pakiranju in niso del na\u0161e ponudbe. Izdelek je namenjen izklju\u010dno za znanstvene in raziskovalne namene.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.royalpeptides.eu\/sl\/produkt\/epithalon-pen-50mg\" \/>\n<meta property=\"og:site_name\" content=\"Royal Peptides\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/profile.php?id=61588101646707\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-19T12:33:24+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.royalpeptides.eu\/wp-content\/uploads\/2026\/06\/Epithalon-pen-50mg-1024x818.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"818\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.royalpeptides.eu\\\/sl\\\/produkt\\\/epithalon-pen-50mg\",\"url\":\"https:\\\/\\\/www.royalpeptides.eu\\\/sl\\\/produkt\\\/epithalon-pen-50mg\",\"name\":\"Epithalon pen 50mg - 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