PEG MGF

Description

PEG-MGF – research peptide (pegylated mechano growth factor)
(Research Use Only)

PEG-MGF is a synthetic pegylated form of mechano growth factor (MGF), which represents an isoform of insulin-like growth factor 1 (IGF-1). Pegylation (attachment of a PEG chain) extends its stability and biological availability under experimental conditions, allowing for more detailed investigation of its effects.

In scientific and preclinical studies, PEG-MGF is used as a tool for analyzing muscle regeneration, cellular proliferation, and adaptive processes to mechanical load.

Mechanistic profile

IGF-1 isoform (Mechano Growth Factor)
PEG-MGF is derived from a naturally occurring isoform of IGF-1 that is activated in response to mechanical damage of muscle tissue.

Satellite cell activation
In laboratory models, its ability to activate muscle satellite cells is studied, as these play a key role in muscle regeneration.

Muscle regeneration
Preclinical studies examine its effect on the repair of damaged muscle fibers and tissue restoration.

⚙ Extended biological activity
Pegylation allows for prolonged action of the molecule under experimental conditions, expanding the possibilities for studying time-dependent effects.

Cellular proliferation and differentiation
Research focuses on its role in regulating cell growth and their differentiation in muscle tissue.

Research advantages

PEG-MGF is mainly used in the areas of:

study of muscle regeneration
analysis of satellite cell activation
research of IGF-1 signaling pathways
modeling of adaptive processes to mechanical load
study of cellular proliferation and differentiation

Scientific background

The biological properties of MGF and its derivatives have been the subject of several scientific studies:

Goldspink G., Journal of Physiology – identification of MGF as a mechanically induced isoform of IGF-1 and its role in muscle adaptation
Yang SY et al., Journal of Muscle Research and Cell Motility – MGF stimulates satellite cell activation and muscle regeneration
Philippou A et al., Growth Hormone & IGF Research – role of IGF-1 isoforms in regulating muscle growth and tissue repair
Hill M., Goldspink G., Journal of Physiology – mechanisms of muscle growth regulation via IGF-1 and MGF
Experimental studies suggest that pegylated forms of peptides may extend biological activity and stability under laboratory conditions

Use in research

PEG-MGF is used in laboratory conditions mainly for:

muscle regeneration research
analysis of IGF-1/MGF signaling pathways
study of cellular proliferation
modeling of muscle tissue damage and repair
experimental cellular and preclinical studies

Safety and regulatory information

PEG-MGF is classified as a research peptide.

❌ Not approved as a medicinal product
❌ Not intended for diagnostic use
❌ Not intended for human or veterinary use

✅ Intended exclusively for laboratory and scientific research

By purchasing the product, the customer confirms that they understand its research nature and agree to use it exclusively in accordance with this intended purpose.

All products available in our offer are intended strictly for research, laboratory, and development purposes only. They are not intended for use as a medicinal product, medical device, cosmetic product, food, dietary supplement, or as an active substance intended for consumption or application in humans or animals.

These products are not approved for clinical use and must not be used for the diagnosis, treatment, or prevention of any disease.

By purchasing the product, the customer acknowledges and confirms understanding of its research nature and agrees to use it exclusively in accordance with this intended purpose.

The purchase of our products is permitted only to individuals over 18 years of age.

Product images are for illustrative purposes only. The actual appearance of the packaging may vary depending on the current batch.