34,90 €
Royal Peptides – KPV 200mcg (60 capsules)
Premium research product containing a high-purity, stabilized tripeptide KPV in oral capsule form for precise laboratory dosing.
KPV (lysine–proline–valine) is a biologically active tripeptide derived from adrenocorticotropic hormone ($alpha$-MSH) that exhibits extremely strong anti-inflammatory, antimicrobial, and cytoprotective properties. The oral capsule form has been specifically developed for advanced gastroenterological research. It is being studied for the potential of KPV to directly target intestinal cells, restore mucosal integrity, suppress localized immune imbalance, and repair the epithelial barrier from within.
The product is intended exclusively for scientific, laboratory, and research purposes.
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KPV – 60 capsules / 200mcg (Advanced Gastrointestinal Repair & Anti-Inflammatory Peptide)
The tripeptide KPV (lysine–proline–valine amino acid sequence) represents in modern regenerative medicine and biomedical research one of the most promising molecules in the field of selective inflammation modulation. It is a natural fragment found in the structure of the $alpha$-melanocyte-stimulating hormone ($alpha$-MSH). Unlike the full molecule of this hormone, KPV does not exhibit any melanotropic activity (does not cause pigmentation or skin darkening), but retains 100% of its anti-inflammatory potential.
The capsule form (200 mcg per capsule, total of 12 mg active substance in the package) is preferred in laboratory protocols for the study of systemic and localized effects in the gastrointestinal tract, where this stable structure can withstand the enzymatic environment and act directly on sites of cellular stress.
Effects Studied in Scientific Research
The primary pillar of research on oral administration of KPV is its unique ability to interact with cellular receptors and transporters (especially via the PepT1 transporter expressed in intestinal cells):
Deep healing and restoration of the intestinal barrier: Research is primarily focused on the ability of KPV to repair intestinal epithelial cells. Its potential to restore so-called “tight junctions” between cells is being studied, which is a key model for leaky gut syndrome research and restoration of intestinal selective permeability.
Targeted suppression of IBD and intestinal inflammation: In in vivo models of chronic inflammatory bowel diseases (such as Crohn’s disease and ulcerative colitis), KPV shows the ability to drastically reduce histological tissue damage. The peptide penetrates directly into cells, where it blocks translocation of NF-$kappa$B (the main transcription factor of inflammation), thereby stopping the production of pro-inflammatory cytokines (TNF-$alpha$, IL-1$beta$, IL-6).
Antimicrobial and antifungal activity: Research data indicate that KPV possesses a natural ability to disrupt the cellular integrity of pathogens. Its effectiveness against the growth of Candida albicans and other opportunistic strains that often colonize a disrupted microbiome is being investigated.
Systemic anti-inflammatory adaptogen: Beyond the gastrointestinal tract, the ability of KPV to suppress autoimmune manifestations, reduce systemic inflammatory markers, and accelerate wound healing and skin pathologies (such as psoriasis or dermatitis) via oral distribution is being studied.
Scientific Context and Research References
The biological mechanism of KPV has been described in detail in leading global gastroenterology and pharmacology journals. Research teams worldwide define it as a safe molecule with zero toxicity, which—unlike corticosteroids—does not broadly suppress the immune system but modulates inflammation intelligently at the level of specific cellular pathways.
Dozens of peer-reviewed publications, including breakthrough studies published in the American Journal of Physiology-Gastrointestinal and Liver Physiology or Biochemical Pharmacology, are available in the international medical database PubMed (search terms: “KPV peptide intestinal inflammation”, “KPV PepT1 transporter” or “KPV NF-kB inhibition”).
Precise data on the stability of this tripeptide in gastric conditions, its pharmacokinetics, and its potential for future human therapeutics for gastrointestinal disorders are continuously collected in international registries on ClinicalTrials.gov.
Royal Peptides packaging contains 60 precisely calibrated capsules with 200 mcg of high-purity KPV, manufactured under strictly controlled laboratory conditions ensuring maximum molecular stability for rigorous scientific research purposes.
⚠️ IMPORTANT NOTICE:
This product is a chemical substance intended exclusively for laboratory, scientific, and research purposes. The product is not a medicine, not a registered food product, not a dietary supplement, and is not intended for human or veterinary use, direct consumption, or therapeutic applications. Improper handling may pose risks. Store in a cool, dry place, out of reach of children.
