Description
Ipamorelin – Dosing Pen 10mg/2ml (Highly Selective GHRP / Ghrelin Mimetic)
Ipamorelin represents one of the most advanced and chemically pure compounds within the group of growth hormone-releasing peptides (GHRPs). It is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that mimics the action of the natural hormone ghrelin. In scientific research, it stands out for its exceptional selectivity – it powerfully stimulates the pituitary gland to produce endogenous growth hormone without affecting the levels of other hormones such as cortisol (the stress hormone), prolactin, or aldosterone. This makes it a fundamental model for studying pure GH secretion without the accompanying undesirable effects associated with earlier generations of peptides.
The dosing pen contains 10 mg of highly purified active substance in 2 ml of solution, corresponding to a concentration of exactly 5 mg/ml. Calculated for precise dosing within research protocols:
1 ml = 100 units (UI) = 100 clicks
0.5 ml (one full rotation of the mechanism) = 50 clicks
Examples of dosing for research purposes:
1 click = 0.05 mg (50 mcg) of active substance
2 clicks = 0.10 mg (100 mcg) of active substance
4 clicks = 0.20 mg (200 mcg) of active substance
10 clicks (0.1 ml) = 0.50 mg (500 mcg) of active substance
20 clicks (0.2 ml) = 1.00 mg (1000 mcg) of active substance
50 clicks (0.5 ml / full rotation) = 2.50 mg (2500 mcg) of active substance
This mechanical system ensures absolute precision, repeatability, and flexibility when setting microdoses according to the requirements of a specific laboratory protocol without the need for complex manual dilution.
Research-Investigated Effects
In the field of cellular biology and metabolic research, Ipamorelin binds to the specific growth hormone secretagogue receptor (GHS-R) in the brain. This binding initiates a signaling cascade that leads to the release of stored growth hormone from the cells of the anterior pituitary gland.
Unlike other compounds in this class, Ipamorelin does not cause a rapid increase in hunger (it does not trigger a sudden release of neuropeptide Y). In vivo studies investigate its ability to stimulate the release of insulin-like growth factor 1 (IGF-1) in the liver. Research data suggest that this axis supports anabolic processes in skeletal muscle, accelerates collagen fiber synthesis, strengthens bone integrity, and significantly shortens the healing time of soft tissues, tendons, and cartilage following mechanical injury. Its positive effect on the breakdown of adipocytes (fat cells) through enhanced lipolysis is also being investigated.
Scientific Context and Sources
The pharmacological profile and high safety of Ipamorelin have been the subject of extensive publications in leading international endocrinology journals, with hundreds of studies indexed in the academic PubMed database. Research teams frequently use it as a comparative standard for evaluating the effectiveness of new selective molecules.
Additional findings regarding its effects on gastrointestinal motility, bone density, and overall metabolic homeostasis are continuously monitored in the ClinicalTrials.gov database, where this compound represents an important pillar of research focused on combating sarcopenia (age-related muscle loss) and other metabolic deficiencies.
The Royal Peptides dosing pen provides a modern, safe, and highly sterile solution for handling this advanced molecule under controlled laboratory conditions.
This product is intended exclusively for scientific and research purposes. Not for direct human consumption.




