Description
Melanotan II – 10mg/2ml Dosing Pen (Melanocortin Receptor Agonist)
Melanotan II (MT-2) is a non-specific, non-selective synthetic cyclic heptapeptide that acts as a potent agonist of melanocortin receptors (specifically MC1, MC3, MC4, and MC5 receptor subtypes). This experimental molecule was developed at the University of Arizona as a more stable and longer-acting alternative to the naturally occurring hormone $alpha$-MSH. In biomedical research, it is widely studied for its ability to penetrate cellular structures and activate a cascade of biochemical processes responsible for the production of the dark pigment eumelanin in melanocytes without requiring excessive exposure of research subjects to carcinogenic UV radiation.
The dosing pen contains 10 mg of highly purified active compound in 2 ml of solution, corresponding to a concentration of exactly 5 mg/ml. For precise dosing within research protocols:
1 ml = 100 units (UI) = 100 clicks
0.5 ml (one full rotation of the mechanism) = 50 clicks
Examples of dosing for research purposes:
1 click = 0.05 mg (50 mcg) of active compound
2 clicks = 0.10 mg (100 mcg) of active compound
4 clicks = 0.20 mg (200 mcg) of active compound
10 clicks (0.1 ml) = 0.50 mg (500 mcg) of active compound
20 clicks (0.2 ml) = 1.00 mg (1000 mcg) of active compound
This mechanical system ensures absolute precision, repeatability, and flexibility when setting microdoses according to the requirements of a specific laboratory protocol without the need for complex manual dilution of concentrates.
Research-Investigated Effects
The primary focus of Melanotan II research is its multi-receptor activity. Binding to MC1 receptors located in the skin initiates melanin synthesis, resulting in tissue darkening, while researchers investigate the potential of this mechanism to protect dermal cells from photodamage and minimize the risk of melanoma development induced by solar radiation.
At the same time, this compound crosses the blood-brain barrier and activates MC3 and MC4 receptors within the central nervous system (primarily in the hypothalamus). In vivo research data suggest that this activation significantly influences energy metabolism, suppresses appetite, and induces satiety. A particularly important area of MT-2 research is its potent effect on the neurogenic stimulation of erectile function and increased libido (through activation of dopaminergic and melanocortin pathways in the brain), which is why it was originally clinically investigated as a potential therapeutic agent for the treatment of sexual dysfunction.
Scientific Background and References
The chemical structure, receptor affinity, and biological effects of Melanotan II are comprehensively documented in dozens of clinical studies available through the internationally respected PubMed database. Research teams continue to investigate its pharmacokinetics, cyclic peptide stability, and comparisons with linear forms (such as Scenesse / Afamelanotide).
Additional findings regarding the influence of the melanocortin system on inflammatory processes, glucose homeostasis, and behavior are continuously collected in academic registries on ClinicalTrials.gov, where this compound remains an important pillar of neuroendocrine research.
The Royal Peptides dosing pen provides a modern, safe, and highly sterile solution for handling this advanced molecule under controlled laboratory conditions.
This product is intended exclusively for scientific and research purposes. Not for direct human consumption.




