Description
NAD+ – Dosing Pen 500mg/2ml (Cellular Coenzyme)
NAD+ is a key coenzyme and redox cofactor that plays an irreplaceable role in the organism in electron transfer and cellular energy production. With increasing age, the level of naturally occurring NAD+ in tissues decreases dramatically, which in modern biomedical research is considered one of the main triggers of mitochondrial dysfunction and cellular aging. This experimental compound is therefore the subject of intensive studies aimed at reversing these effects through activation of sirtuins (so-called “longevity genes”) and enzymes involved in genome protection.
The dosing pen contains 500 mg of highly pure and stabilized active substance in 2 ml of solution, representing a high concentration of exactly 250 mg/ml. Conversion for precise dosing within research protocols:
1 ml = 100 units (IU) = 100 clicks
0.5 ml (one full rotation of the mechanism) = 50 clicks
Examples of research dosing:
1 click = 2.50 mg of active substance
2 clicks = 5.00 mg of active substance
10 clicks (0.1 ml) = 25.00 mg of active substance
20 clicks (0.2 ml) = 50.00 mg of active substance
40 clicks (0.4 ml) = 100.00 mg of active substance
50 clicks (0.5 ml / full rotation) = 125.00 mg of active substance
This mechanical system ensures absolute precision, repeatability, and flexibility when setting microdoses according to the needs of a specific laboratory protocol without the need for complex manual dilution of concentrates.
Effects Studied in Research
In the field of metabolic and neurological research, NAD+ is studied for its ability to radically optimize mitochondrial function – the energy centers of cells. Its presence is critical for the conversion of nutrients into ATP (adenosine triphosphate), the body’s primary energy currency.
In vivo studies suggest that restoring optimal NAD+ levels activates sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3). These proteins regulate metabolic flexibility, suppress chronic intracellular inflammation, and protect cells from oxidative stress. Another important area of research is neuroprotection – scientists are studying the effect of NAD+ on cognitive function, nerve pathway regeneration, mental clarity, and the elimination of chronic fatigue at the cellular level. Its synergy with PARP enzymes, which repair breaks in DNA strands, is also being investigated.
Scientific Context and References
The role of NAD+ in cellular biology is among the most frequently published topics in leading academic journals such as Science and Nature, as well as in databases indexed in PubMed. Research teams worldwide confirm a direct correlation between systemic increases in the availability of this coenzyme and the extension of healthy cellular lifespan (healthspan).
Detailed information on the impact of NAD+ supplementation on metabolic syndrome, insulin sensitivity, and muscle tissue regeneration is continuously collected in clinical proposals on ClinicalTrials.gov, where this molecule represents a fundamental pillar of modern longevity medicine and longevity research.
The Royal Peptides dosing pen provides a modern, safe, and highly sterile solution for handling this advanced molecule under controlled laboratory conditions.
This product is intended exclusively for scientific and research purposes. Not for direct human consumption.




